890808-56-7
Chemical Structure
M47
- CAS No.: 890808-56-7
- Formula:C28H22ClNO4
- Molecular Weight:471.93
IUPAC Name: 7-hydroxy-8-methoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
InChIKey: HUWLQJUHXIKAIW-UHFFFAOYSA-N
SMILES: O=C(N1C2=C(CC1)C=CC=C2)C(OC3=CC=C4OC(C)(C5)C6=CC=C(C=C6)Cl)=C(C)C3=C4C5=O
Biological Activity: M47 is a molecular glue that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer[1].
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M47 | 99.96% | M47 is a molecular glue that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer. | ||||||||||||||||||||
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Keywords
