12 Results for "

nicotine metabolism

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "nicotine metabolism" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-B0143A
CAS No.: 636-79-3
Synonyms: Nicotinic acid hydrochloride; Vitamin B3 hydrochloride
Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases .
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Cat. No.: HY-W104368
CAS No.: 17720-18-2
Nicotinic acid riboside is a NAD + precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD + metabolism .
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Cat. No.: HY-121027
CAS No.: 486-89-5
Purity:  98.15%
Synonyms: (-)-Anagyrine; Monolupine; Rhombinine
Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective desensitizer of nAChR, and Anagyrine can directly, without metabolism, desensitize nAChR .
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Cat. No.: HY-155456
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease

CD-6 is a flavonoid CYP2A6 inhibitor (IC50: 1.566 μM). CYP2A6 inhibits the metabolism of nicotine to cotinine, resulting in an increase in the amount of nicotine available in the blood, leading to increased smoking behavior. CD-6 mediates CYP2A6 inhibition and can be used in research on smoking cessation or smoking-related diseases .
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Cat. No.: HY-W015467
CAS No.: 636-73-7
Synonyms: Pyridine-3-sulphonic acid
Pyridine-3-sulfonic acid (Pyridine-3-sulphonic acid) is an orally active structural analog of Nicotine acid (HY-B0143). Pyridine-3-sulfonic acid significantly reduces hepatic cholesterol synthesis in rats but lacks cholesterol-lowering activity. Pyridine-3-sulfonic acid does not interfere with the metabolism of Nicotine acid .
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Cat. No.: HY-W856819
CAS No.: 469-22-7
Eseroline is a potent μ-opioid receptor agonist, which is the hydrolytic metabolite of Physostigmine (HY-N6608). Eseroline is a selective and competitive acetylcholinesterase (AChE) inhibitor, with its Ki values for AChE and BuChE being 0.1 μM and 200 μM respectively. Eseroline has nicotinic acetylcholine receptor allosteric enhancing ligand (nAChR-APL) activity, meaning it does not activate the receptor but significantly enhances the signal transduction of Ach triggered by the receptor. Eseroline is neurotoxic, causing cell membrane damage (LDH leakage) and energy metabolism collapse (ATP depletion). Eseroline can be used for the study of Alzheimer's disease .
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Cat. No.: HY-W742088
Nicotinic acid riboside-d4 is the deuterium labeled Nicotinic acid riboside (HY-W104368). Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism .
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Cat. No.: HY-160251
CAS No.: 132929-88-5
Synonyms: (3'R,5k'S)-trans-3'-Hydroxycotinine glucuronide
Target:  

Drug Metabolite

Research Areas:  

Others

3-HC-Gluc ((3’R,5k’s)-trans-3’ -Hydroxycotinine glucuronide) The trans-structure of 3-HC, the main metabolite of nicotine .
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Cat. No.: HY-121027A
CAS No.: 74195-83-8
Synonyms: (-)-Anagyrine hydrochloride; Monolupine hydrochloride; Rhombinine hydrochloride
Anagyrine ((-)-Anagyrine) hydrochloride is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine hydrochloride binds to muscarinic and nicotinic acetylcholine receptors with IC50 values of 132 and 2096 µM respectively. Anagyrine hydrochloride is a potent and effective desensitizer of nAChR, and Anagyrine hydrochloride can directly, without metabolism, desensitize nAChR .
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Cat. No.: HY-W104368R
CAS No.: 17720-18-2
Nicotinic acid riboside (Standard) is the analytical standard of Nicotinic acid riboside (HY-W104368). This product is intended for research and analytical applications. Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism .
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Cat. No.: HY-P3241A
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Nucleoside Phosphorylase, bacterial (EC 2.4.2.1), is a pentosesyltransferase. Nucleoside Phosphorylase participates in three metabolic pathways: purine metabolism, pyrimidine metabolism, and nicotinic acid and nicotinamide metabolism. Its two substrates are purine nucleosides and phosphates, and its two products are purines and α-D-ribose-1-phosphate.
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Cat. No.: HY-W795548
CAS No.: 713-05-3
Target:  

Endogenous Metabolite

Research Areas:  

Others

N-Methyl-4-oxo-4-(pyridin-3-yl) butanamide is a urinary metabolite of (±)-Cotinine in rats and an intermediate in the bacterial catabolism of Nicotine. N-Methyl-4-oxo-4-(pyridin-3-yl) butanamide serves as a tool molecule for studies on Nicotine metabolism.
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