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Results for "

oat

" in MedChemExpress (MCE) Product Catalog:

By Targets:	OAT (18) 11β-HSD (1) Acetolactate Synthase (ALS) (2) Acyltransferase (3) Antibiotic (1) Bacterial (1) BCRP (3) Deubiquitinase (1) Drug Derivative (2) Drug Metabolite (1) Endogenous Metabolite (3) Environmental Pollutants (6) Fluorescent Dye (1) Fungal (1) GLUT (1) Glycosidase (2) Herbicide (5) HIV (3) HIV Integrase (3) Interleukin Related (1) Isotope-Labeled Compounds (1) Oct3/4 (1) P-glycoprotein (1) Parasite (2) Reference Standards (6) Small Interfering RNA (siRNA) (3) URAT1 (7)
By Research Areas:	Cancer (4) Infection (10) Inflammation/Immunology (8) Metabolic Disease (16) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: OAT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15592

Cabotegravir Maximum Cited Publications 14 Publications Verification GSK-1265744; S/GSK1265744	OAT HIV HIV Integrase	Infection
Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC₅₀ values of 2.5 nM, 0.41 μM and 0.81 μM for HIV_ADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS .

HY-16278

Pradigastat 2 Publications Verification LCQ-908	Acyltransferase BCRP OAT	Infection Metabolic Disease
Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC₅₀ at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC₅₀ of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro .

HY-113493

4-Pyridoxic acid	Endogenous Metabolite	Metabolic Disease
4-Pyridoxic acid is an endogenous substrate of renal organic anion transporters (OAT1/3) and a catabolite of vitamin B6. 4-Pyridoxic acid is excreted through OAT1/3-mediated tubular active secretion, which can reflect OAT1/3 activity. Elevated plasma concentrations of 4-Pyridoxic acid are associated with decreased OAT1/3 activity in chronic kidney disease (CKD) and can be used as a biomarker to reflect the severity of knee osteoarthritis (KOA) and lumbar spondylosis (LS) .

HY-15258

Lesinurad 5 Publications Verification RDEA594	OAT URAT1	Metabolic Disease
Lesinurad is a URAT1 and *OAT* inhibitor, is determined to be a substrate for the kidney transporters *OAT1* and *OAT3* with K_m values of 0.85 and 2 µM, respectively.

HY-122009

Indican Indoxyl-β-D-glucoside	P-glycoprotein OAT Fluorescent Dye	Others
Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .

HY-118693

Avenanthramide D Dianthramide P	Drug Derivative	Inflammation/Immunology
Avenanthramide D is a phenolic acids found in the Avena sativa L.. Avenanthramide D is promising for research of inflammation .

HY-15592A

Cabotegravir sodium Maximum Cited Publications 14 Publications Verification GSK-1265744 sodium; S/GSK1265744 sodium	OAT HIV HIV Integrase	Infection
Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC₅₀ values of 2.5 nM, 0.41 μM and 0.81 μM for HIV_ADA, OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir sodium can be used to research AIDS .

HY-N4103A

Δ5-Avenasterol	Others	Cancer
Δ5-Avenasterol, belongs to the components of oat grain , exhibits propounding antioxidant effectiveness .

HY-15258A

Lesinurad sodium 5 Publications Verification RDEA-594 sodium	OAT URAT1	Metabolic Disease
Lesinurad sodium is a URAT1 and *OAT* inhibitor, is determined to be a substrate for the kidney transporters *OAT1* and *OAT3* with K_m values of 0.85 and 2 μM, respectively.

HY-W014118

α-Hexylcinnamaldehyde	Environmental Pollutants	Inflammation/Immunology Cancer
α-Hexylcinnamaldehyde is an O-acetyltransferase (OAT) inhibitor. α-Hexylcinnamaldehyde inhibits *OAT*-mediated bioactivation of nitroarene mutagens, exerts antimutagenic activity through demutagenic and bioantimutagenic mechanisms, and interferes with ATP-binding cassette (ABC) transporter function to reduce substrate efflux. α-Hexylcinnamaldehyde alters membrane permeability, fluidizes phospholipid membranes, exerts antioxidant effects, and enhances the antiproliferative effect of Doxorubicin on human cancer cells. α-Hexylcinnamaldehyde can be used in the research of colorectal adenocarcinoma, T-cell leukemia, and multidrug-resistant cancers .

HY-154021A

5-Fluoromethylornithine dihydrochloride 5-FMOrn dihydrochloride	OAT	Metabolic Disease
5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina .

HY-124344

Avenanthramide C	Interleukin Related	Neurological Disease
Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β(Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimer’s disease .

HY-119435

Triallate	Herbicide Environmental Pollutants	Others
Triallate is a selective thiocarbamate herbicide. Triallate regulates the biosynthesis of very-long-chain fatty acids and inhibits the elongation and division of plant cells. Triallate is used to control wild oats in barley, spring wheat, durum wheat, winter wheat and sugar beets .

HY-133825

Cyazofamid IKF-916	Environmental Pollutants OAT Oct3/4	Infection
Cyazofamid exerts its bactericidal effect by impairing ATP production. Cyazofamid inhibits organic cation transporter 3 (OCT3) and *OAT1, with IC₅₀* values of 1.54 and 17.3 μM, respectively .

HY-126987

Mesosulfuron-methyl	Environmental Pollutants Acetolactate Synthase (ALS)	Others
Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields .

HY-148682

18β-Glycyrrhetyl-3-O-sulfate Glycyrrhetic acid 3-O-hydrogen sulfate	OAT 11β-HSD Drug Metabolite	Metabolic Disease Inflammation/Immunology
18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) inhibitor with an IC₅₀ of 0.10 µM using rat kidney microsome. 18β-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18β-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18β-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research .

HY-111345

Epaminurad UR-1102; URC-102	OAT URAT1	Metabolic Disease Inflammation/Immunology
Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a K_i of 0.057 μM. Epaminurad quite modestly inhibits *OAT1* and *OAT3* (organic anion transporter). Epaminurad is a uricosuric agent. Epaminurad can be used for gout and hyperuricemia research .

HY-N9693

Gibberellin A8	Drug Derivative	Metabolic Disease
Gibberellin A8 is a derivative of Gibberellic acid (HY-N1964), a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellin A8 shows a weak growth-promoting activity on rice seedlings and oat mesocot .

HY-120107

OAT-177	Parasite	Inflammation/Immunology
OAT-177 is a potent dual inhibitor targeting acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with an IC₅₀=14.2 nM for human AMCase and IC₅₀=232 nM for human CHIT1. OAT-177 is promising for research of chronic inflammatory and fibrotic-related lung diseases such as asthma and idiopathic pulmonary fibrosis .

HY-N8279

β-1,3-1,4-Glucanase Endo-β-1,3-1,4-glucanase	Glycosidase	Metabolic Disease
β-1,3-1,4-glucanase (Endo-β-1,3-1,4-glucanase) is a glycoside hydrolase family 16 enzyme (some members belong to subfamily 25). β-1,3-1,4-glucanase shows high substrate specificity toward mixed‑linked β‑glucans and cleaves β‑1,4 glycosidic bonds adjacent to β‑1,3 linkages in an endo‑type pattern. β-1,3-1,4-glucanase can be used in industrial enzyme applications and monogastric animal feed supplementation .

HY-15592R

Cabotegravir (Standard) GSK-1265744 (Standard); S/GSK1265744 (Standard)	OAT Reference Standards HIV HIV Integrase	Infection
Cabotegravir (Standard) is the analytical standard of Cabotegravir. This product is intended for research and analytical applications. Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC₅₀ values of 2.5 nM, 0.41 μM and 0.81 μM for HIV_ADA, OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS .

HY-W740244

4’-Hydroxy Trazodone	OAT	Metabolic Disease
4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone. It is an inhibitor of organic anion transporter 3 (OAT3; Ki=16.9 μM) and is selective for OAT3 over OAT1 (Ki=>200 μM).

HY-111345A

Epaminurad hydrochloride UR-1102 hydrochloride; URC-102 hydrochloride	OAT URAT1	Metabolic Disease Inflammation/Immunology
Epaminurad (UR-1102) hydrochloride is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a K_i of 0.057 μM. Epaminurad hydrochloride quite modestly inhibits *OAT1* and *OAT3* (organic anion transporter). Epaminurad hydrochloride is a uricosuric agent. Epaminurad hydrochloride can be used for gout and hyperuricemia research .

HY-144305

KPH2f	URAT1 GLUT	Infection
KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC₅₀s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC₅₀=32.14 and 26.74 μM) .

HY-N12008

OAT1/3-IN-2	OAT	Metabolic Disease
OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage .

HY-N12007

OAT1/3-IN-1	OAT	Metabolic Disease
OAT1/3-IN-1 (compound 7) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-1 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-1 can be used to study mercury-induced kidney damage .

HY-125279

OAT-2068	Parasite	Inflammation/Immunology
OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC₅₀=29 nM) and displays 143-fold selectivity over m AMCase (IC₅₀=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases .

HY-RS16776

Oat Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Oat Mouse Pre-designed siRNA Set A contains three designed siRNAs for Oat gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Oat Mouse Pre-designed siRNA Set A Oat Mouse Pre-designed siRNA Set A

HY-RS09731

OAT Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
OAT Human Pre-designed siRNA Set A contains three designed siRNAs for OAT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

OAT Human Pre-designed siRNA Set A OAT Human Pre-designed siRNA Set A

HY-15258S1

Lesinurad-d4 RDEA594-d₄	Isotope-Labeled Compounds URAT1 OAT	Metabolic Disease
Lesinurad-d₄ (RDEA594-d₄) is deuterium labeled Lesinurad. Lesinurad is a URAT1 and *OAT* inhibitor, is determined to be a substrate for the kidney transporters *OAT1* and *OAT3* with K_m values of 0.85 and 2 μM, respectively.

HY-129493

Lateropyrone	Bacterial Antibiotic Endogenous Metabolite	Infection
Lateropyrone is a type of pyranone antibiotic that can inhibit Gram-negative bacteria, and it's a secondary metabolite produced by the oat fungal pathogen .

HY-136367

Diclofop-methyl	Environmental Pollutants Herbicide	Others
Diclofop-methyl, a common post-emergence herbicide, is widely used in agriculture production. Diclofop-methyl increases the proton permeability of isolated oat-root tonoplast .

HY-163431

URAT1 inhibitor 10	URAT1	Inflammation/Immunology
URAT1 inhibitor 10 (Compound 23a) is a URAT1 inhibitor. URAT1 inhibitor 10 has oral efficacy and low cytotoxicity. URAT1 inhibitor 10 has high selectivity for *OAT1* .

HY-W014118R

α-Hexylcinnamaldehyde (Standard)	Reference Standards Environmental Pollutants	Cancer
α-Hexylcinnamaldehyde (Standard) is the analytical standard of α-Hexylcinnamaldehyde. This product is intended for research and analytical applications. α-Hexylcinnamaldehyde is an O-acetyltransferase (OAT) inhibitor. α-Hexylcinnamaldehyde inhibits *OAT*-mediated bioactivation of nitroarene mutagens, exerts antimutagenic activity through demutagenic and bioantimutagenic mechanisms, and interferes with ATP-binding cassette (ABC) transporter function to reduce substrate efflux. α-Hexylcinnamaldehyde alters membrane permeability, fluidizes phospholipid membranes, exerts antioxidant effects, and enhances the antiproliferative effect of Doxorubicin on human cancer cells. α-Hexylcinnamaldehyde can be used in the research of colorectal adenocarcinoma, T-cell leukemia, and multidrug-resistant cancers .

HY-126987R

Mesosulfuron-methyl (Standard)	Acetolactate Synthase (ALS) Reference Standards	Others
Mesosulfuron-methyl (Standard) is the analytical standard of Mesosulfuron-methyl. This product is intended for research and analytical applications. Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields .

HY-N15726

Obtusichromoneside C	Others	Others
Obtusichromoneside C is a chromone C-glycoside found in the seeds of Cassia obtusifolia. Obtusichromoneside C regulates substance transport by inhibiting substrate uptake of specific transporters (e.g., OAT3, OATP1B3). Obtusichromoneside C is promising for research of drug transport .

HY-180321

OAT-1441	Glycosidase	Others
OAT-1441 is a selective hAMCase inhibitor with oral activity (IC₅₀ = 7 nM). OAT-1441 can be used to study the physiological functions of hAMC enzymes .

HY-183689

OAT-4828	Deubiquitinase	Cancer
OAT-4828 is an orally active ubiquitin-specific protease 7 (USP7) inhibitor with an IC₅₀ of 32 nM. OAT-4828 induces antileukemic activity in B-cell-derived non-Hodgkin's lymphoma models via inhibition of USP7. OAT-4828 is applicable to research related to chronic lymphocytic leukemia .

HY-W714171

Propoxycarbazone sodium BAY MKH 6561	Herbicide	Others
Propoxycarbazone sodium (BAY MKH 6561) is a herbicide. Propoxycarbazone sodium controls shepherd’s purse (Capsella bursa-pastoris L. Medicus), tumble mustard (Sisymbrium altissimum L.), field pennycress (Thlaspi arvense L.), and several Bromus species. Propoxycarbazone sodium also inhibits the growth of jointed goatgrass, wild oat (Avena fatua L.), and quackgrass (Elytrigia repens L. Nevski) .

HY-W714171R

Propoxycarbazone sodium (Standard) BAY MKH 6561 (Standard)	Herbicide Reference Standards	Others
Propoxycarbazone (sodium) (Standard) is the analytical standard of Propoxycarbazone (sodium). This product is intended for research and analytical applications. Propoxycarbazone sodium (BAY MKH 6561) is a herbicide. Propoxycarbazone sodium controls shepherd’s purse (Capsella bursa-pastoris L. Medicus), tumble mustard (Sisymbrium altissimum L.), field pennycress (Thlaspi arvense L.), and several Bromus species. Propoxycarbazone sodium also inhibits the growth of jointed goatgrass, wild oat (Avena fatua L.), and quackgrass (Elytrigia repens L. Nevski) .

HY-16278A

Pradigastat sodium LCQ 908 sodium	Acyltransferase BCRP OAT	Infection Metabolic Disease
Pradigastat sodium (LCQ 908 sodium) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC₅₀ at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC₅₀ of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro .

HY-16278R

Pradigastat (Standard) LCQ-908 (Standard)	Acyltransferase BCRP OAT Reference Standards	Infection Metabolic Disease
Pradigastat (Standard) is the analytical standard of Pradigastat. This product is intended for research and analytical applications. Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC50 at 0.157 µM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC50 of 5 µM, 1.66µM, 3.34µM and 0.973µM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro .

HY-RS23216

Oat Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Oat Rat Pre-designed siRNA Set A contains three designed siRNAs for Oat gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Oat Rat Pre-designed siRNA Set A Oat Rat Pre-designed siRNA Set A

HY-N18069

Avenanthramide L	Fungal Endogenous Metabolite	Infection
Avenanthramide L is a phytoalexin that can inhibit the spore germination of Puccinia coronata f. sp. avenae. Avenanthramide L is found in the leaves of inoculated oats, but not in the leaves of healthy oat seedlings, and at a concentration of 200-300 μg/mL. Avenanthramide L inhibits fungal spore germination by up to 50%. Avenanthramide L is absent from the leaves of healthy oat seedlings. Avenanthramide L can be used for the research of oat crown rust .

HY-N18679

Avena sativa kernel extract	Others	Others
Avena sativa kernel extract is extracted from the kernel of the oat plant, a member of the Poaceae family. Its main active ingredient is glucan, a high-sugar substance that can form a transparent, elastic, and breathable film on the skin.

HY-136367R

Diclofop-methyl (Standard)	Herbicide Reference Standards	Others
Diclofop-methyl (Standard) is the analytical standard of Diclofop-methyl. This product is intended for research and analytical applications. Diclofop-methyl, a common post-emergence herbicide, is widely used in agriculture production. Diclofop-methyl increases the proton permeability of isolated oat-root tonoplast .

Cat. No.	Product Name	Category	Target	Chemical Structure