Δ5-Avenasterol
Based on 1 Customer Validation
Δ5-Avenasterol is an antioxidant that targets cyclooxygenase-2 (COX-2) and exists in tomato seed oil, oat grain oil, and wheat germ oil. Δ5-Avenasterol binds to the active site of COX-2, thereby blocking the conversion of arachidonic acid to inflammatory prostaglandins. Δ5-Avenasterol exerts antioxidant activity via the ethylene group at positions 24 and 28 of its side chain.
For research use only. We do not sell to patients.
- Purity : 98.01%
- CAS No.: 18472-36-1
- Formula: C29H48O
- Molecular Weight:412.69
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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5α-Cholestane -
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Biological Activity
Description
IC50 & Target
[1]|
COX-2 |
In Vitro
Δ5-Avenasterol binds to human COX-2 with high affinity (-10.7 kcal/mol), indicating potential antiinflammatory activity through inhibition of this key inflammatory enzyme[1].
Δ5-Avenasterol contributes to the antioxidant properties of unsaponifiable matter from its source oils and ranks among oat grain’s highest antioxidant components[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 18472-36-1
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Appearance Solid
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Molecular Weight 412.69
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Formula C29H48O
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Color White to off-white
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SMILES
C/C=C(C(C)C)/CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (279 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Δ5-Avenasterol Related Classifications
HY-N4103A Related Classifications
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