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  4. 5-Fluoromethylornithine dihydrochloride

5-Fluoromethylornithine dihydrochloride  (Synonyms: 5-FMOrn dihydrochloride)

Cat. No.: HY-154021A Purity: ≥95.0%
COA Handling Instructions

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5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina.

For research use only. We do not sell to patients.

5-Fluoromethylornithine dihydrochloride Chemical Structure

5-Fluoromethylornithine dihydrochloride Chemical Structure

CAS No. : 124796-41-4

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5 mg USD 430 In-stock
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Based on 1 publication(s) in Google Scholar

5-Fluoromethylornithine dihydrochloride Related Antibodies

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Description

5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina[1][2].

Molecular Weight

237.10

Formula

C6H15Cl2FN2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC(CCC(N)CF)C(O)=O.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (421.76 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2176 mL 21.0881 mL 42.1763 mL
5 mM 0.8435 mL 4.2176 mL 8.4353 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥95.0%

COA (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.2176 mL 21.0881 mL 42.1763 mL 105.4407 mL
5 mM 0.8435 mL 4.2176 mL 8.4353 mL 21.0881 mL
10 mM 0.4218 mL 2.1088 mL 4.2176 mL 10.5441 mL
15 mM 0.2812 mL 1.4059 mL 2.8118 mL 7.0294 mL
20 mM 0.2109 mL 1.0544 mL 2.1088 mL 5.2720 mL
25 mM 0.1687 mL 0.8435 mL 1.6871 mL 4.2176 mL
30 mM 0.1406 mL 0.7029 mL 1.4059 mL 3.5147 mL
40 mM 0.1054 mL 0.5272 mL 1.0544 mL 2.6360 mL
50 mM 0.0844 mL 0.4218 mL 0.8435 mL 2.1088 mL
60 mM 0.0703 mL 0.3515 mL 0.7029 mL 1.7573 mL
80 mM 0.0527 mL 0.2636 mL 0.5272 mL 1.3180 mL
100 mM 0.0422 mL 0.2109 mL 0.4218 mL 1.0544 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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5-Fluoromethylornithine dihydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Fluoromethylornithine124796-41-45-FMOrnBiochemical Assay Reagentsgyrate atrophy of choroid and retinaInhibitorinhibitorinhibit

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