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Results for "

peroxidase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Glutathione Peroxidase (49) ACSL Family (1) Adrenergic Receptor (1) Amyloid-β (1) Antibiotic (4) Apoptosis (14) Autophagy (4) Bacterial (12) Bcl-2 Family (2) Biochemical Assay Reagents (25) Calcium Channel (1) Cannabinoid Receptor (1) Carboxylesterase (CES) (1) Caspase (3) Cholinesterase (ChE) (3) COX (7) Cytochrome P450 (2) DNA Stain (4) DNA/RNA Synthesis (3) Drug Derivative (1) Drug Intermediate (1) Drug Isomer (2) Drug Metabolite (4) Endogenous Metabolite (20) Environmental Pollutants (5) Ferroptosis (34) Fluorescent Dye (35) Fungal (3) Glutathione Reductase (GR) (3) Glutathione S-transferase (1) Herbicide (1) HIV (1) Influenza Virus (1) Insecticide (1) Interleukin Related (2) Isotope-Labeled Compounds (8) LDLR (3) Lipoxygenase (1) LXR (1) MDM-2/p53 (2) Mitochondrial Metabolism (3) Mitophagy (3) MOFs (1) NADPH Oxidase (1) Oxidative Phosphorylation (1) p38 MAPK (3) p62 (2) Phosphatase (1) Phytohormone (1) PI3K (1) PKC (1) Potassium Channel (1) PPAR (1) PROTACs (1) Reactive Oxygen Species (ROS) (35) Reference Standards (18) Sirtuin (2) SOD (11) STING (1) Tau Protein (3) TMV (1) TNF Receptor (2) Transferrin Receptor (1) TrxR (1) Tyrosinase (1) UGT (2) VAP-1 (1) Virus Protease (2) YAP (1)
By Research Areas:	Cancer (38) Cardiovascular Disease (9) Endocrinology (6) Infection (18) Inflammation/Immunology (35) Metabolic Disease (31) Neurological Disease (21)
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190

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Click Chemistry

Targets Recommended: Peroxidase Enzyme Glutathione Peroxidase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-125859

Peroxidase, Horseradish 1 Publications Verification	Reactive Oxygen Species (ROS)	Inflammation/Immunology Endocrinology
Peroxidase, Horseradish actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases .

HY-13750

Ebselen 20+ Cited Publications SPI-1005; PZ-51; CCG-39161	Calcium Channel Virus Protease HIV Phosphatase	Infection Neurological Disease Inflammation/Immunology Cancer
Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker . Ebselen potently inhibits M ^pro (IC₅₀=0.67 μM) and COVID-19 virus (EC₅₀=4.67 μM) .Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity .

HY-15902

ABTS diammonium salt Maximum Cited Publications 13 Publications Verification AzBTS-(NH4)2	Fluorescent Dye	Others
ABTS diammonium salt (AzBTS-(NH4)2) is a substrate for horseradish peroxidase (HRP) conjugate. ABTS diammonium salt can be used to evaluate antioxidant capacity .

HY-B0329

Isoniazid 10+ Cited Publications INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .

HY-100003

ML-210 25+ Cited Publications	Glutathione Peroxidase Ferroptosis	Cancer
ML-210 is a selective and covalent *glutathione peroxidase* 4 (GPX4) inhibitor with an EC₅₀** of 30 nM. ML-210 binds the GPX4 selenocysteine residue. ML-210 has anti-cancer activity .

HY-101880

ADHP 2 Publications Verification 10-Acetyl-3,7-dihydroxyphenoxazine	Fluorescent Dye	Others
ADHP is a fluorogenic peroxidase substrate (λ_ex=530 nm, λ_em=590 nm).

HY-100002

ML162 10+ Cited Publications	Glutathione Peroxidase Ferroptosis	Cancer
ML162 is a covalent *glutathione peroxidase* 4 (GPX4)** inhibitor. ML162 has a selective lethal effect on mutant RAS oncogene-expressing cell lines

HY-135849A

Catalase, Bovine Liver	Reactive Oxygen Species (ROS)	Others Cancer
Catalase, Bovine Liver is an enzyme widely found in various organisms, including animals, plants and microorganisms. Catalase, Bovine Liver mainly exists in the peroxisome of cells and is an important antioxidant enzyme. Catalase, Bovine Liver plays an important role in removing ROS and maintaining the balance of redox state. Catalase, Bovine Liver is closely related to the occurrence and development of tumors. Catalase, Bovine Liver has the potential to be used in tumor prevention research .

HY-138153

JKE-1674 5+ Cited Publications	Glutathione Peroxidase Ferroptosis	Cancer
JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and an active metabolite of GPX4 inhibitor ML-210. JKE-1674, an analog of ML-210 in which the nitroisoxazole ring is replaced with an α-nitroketoxime. JKE-1674 can convert into a nitrile oxide JKE-1777. JKE-1674 kills LOX-IMVI cells in a manner that is equipotent to ML-210 and is completely rescued by ferroptosis inhibitors .

HY-B1000A

L-SelenoMethionine 5 Publications Verification	Endogenous Metabolite Apoptosis	Cancer
L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-D1840

Tyramide Amplification Buffer 1 Publications Verification	Biochemical Assay Reagents	Others
Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). Tyramide Amplification Buffer enables the reaction between tyramide-labeled antibodies and fluorescently labeled tyramide substitutes (tyramide) using peroxidase, resulting in a highly amplified fluorescent signal. Tyramide Amplification Buffer can be used for signal enhancement in detection methods such as immunofluorescence (IF), immunohistochemistry (IHC), or in situ hybridization (FISH) .

HY-W012145

TMPD dihydrochloride	Others	Metabolic Disease
TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases . TMPD dihydrochloride is also a complex IV substrate .

HY-P2833

Glutathione Peroxidase GSH-Px; EC 1.11.1.9	Glutathione Peroxidase	Metabolic Disease
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H₂O. Glutathione Peroxidase is an effective antioxidant against oxidative stress .

HY-15914

DHBS DCHBS	Fluorescent Dye	Others
DHBS (3, 5-dichloro-2-hydroxybenzenesulfonate) is used in conjunction with 4-aminoantipyrine (4-AAP) (HY-W100990) and hydrogen peroxide (H₂O₂) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems .

HY-141809

GPX4-IN-3 2 Publications Verification	Glutathione Peroxidase Ferroptosis	Cancer
GPX4-IN-3 (26a) is a potent *glutathione peroxidase* 4 (GPX4) inhibitor as a selective ferroptosis** inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM .

HY-E70336

Peroxidase, Lignin	Endogenous Metabolite	Others
Peroxidase, Lignin is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-E70387

Ligninase	Endogenous Metabolite	Others
Ligninase is a general term for extracellular heme-containing peroxidases produced by Phanerochaete chrysosporium. Ligninase can catalyze lignin degradation. Ligninase can be used in waste treatment and detoxification of environmental pollutants .

HY-W143216

Azure C Monomethylthionine	Amyloid-β Tau Protein	Neurological Disease
Azure C acts as a tau oligomer modulator and Aβ42 oligomerization inhibitor. It regulates hsp70 ATPase activity, thereby mediating the clearance of tau protein. Azure C reduces the levels of toxic tau oligomers by promoting the formation of non-toxic tau aggregates, rescues neuroblastoma cells from tau oligomer-induced toxicity, and binds to and inhibits Aβ42 oligomerization without suppressing its fibrillization. Azure C is generated via sequential oxidation of methylene blue or Azure B through a horseradish peroxidase-mediated reaction, and accumulates in HRP reaction media. Azure C can be used in studies related to tauopathies, including Alzheimer's disease .

HY-N0859

Schisanhenol Schizanhenol; Gomisin-K3	UGT Cholinesterase (ChE) Tau Protein SOD Sirtuin	Neurological Disease Inflammation/Immunology Cancer
Schisanhenol (Schizanhenol), a lignan, is an orally active antioxidant. Schisanhenol reduces AChE activity, increases SIRT1 and PGC-1α expression, and decreases phosphorylated Tau (Ser 396) levels. Schisanhenol increases SOD and glutathione peroxidase activity, decreases malondialdehyde (MDA) content, and inhibits UGT2B7 activitY. Schisanhenol attenuates ox-LDL-induced apoptosis, intracellular reactive oxygen species generation, and cytotoxicity in endothelial cells. Schisanhenol inhibits LDL oxidation, brain mitochondrial and membrane peroxidative damage, and brain mitochondrial swelling and disintegration. Schisanhenol can be used for the research of Alzheimer’s disease, atherosclerosis, brain ischemia, and age-related brain deterioration .

HY-107858

Veratryl alcohol 1 Publications Verification 3,4-Dimethoxybenzyl alcohol	Endogenous Metabolite Bacterial	Infection
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H₂O₂ and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .

HY-A0278

Hexaconazole (-)-Hexaconazol	Environmental Pollutants Reactive Oxygen Species (ROS) Fungal SOD	Infection Endocrinology
Hexaconazole is a demethylation enzyme inhibitor and a synthetic fungicide that targets many fungi, especially ascomycetes and basidiomycetes, and it can enhance the activity of SOD and *peroxidase*. Hexaconazole causes endocrine disorders in zebrafish larvae .

HY-125859B

Lactoperoxidase, bovine milk	Bacterial	Infection
Lactoperoxidase, bovine milk is an antimicrobial protein that belongs to the mammalian heme peroxidase family. Lactoperoxidase, bovine milk uses H₂O₂ to catalyze the oxidation of its preferred halide substrates including I ⁻, Br ⁻, F ⁻, or the pseudohalide SCN ⁻ .

HY-B2235C

L-α-Lecithin (soybean)	Biochemical Assay Reagents Glutathione Peroxidase	Metabolic Disease
L-α-Lecithin (soybean) is an orally active phospholipid. L-α-Lecithin (soybean) increases the bioavailability of Lutein in plasma and eyes of Rattus norvegicus, enhances plasma Glutathione peroxidase activity, and regulates fatty acids in plasma and tissues .

HY-N3031

Grosvenorine	Bacterial Apoptosis Bcl-2 Family MDM-2/p53 Glutathione Peroxidase SOD TNF Receptor Interleukin Related	Infection Inflammation/Immunology
Grosvenorine is an orally active flavonoid glycoside found in S. grosvenorii. Grosvenorine exhibits antibacterial, antioxidant and antiinflammation activities. Grosvenorine can induce apoptosis and increases anti-apoptotic Bcl-2 protein expression and reduces pro-apoptotic P53 protein expression in gastric tissues. Grosvenorine enhances mucin/glycoprotein secretion, regulates gastric pH, and reduces gastric lesion incidence.Grosvenorine increases glutathione peroxidase, catalase, and SOD levels, reduces lipid peroxidation (MDA), and lowers TNF-α and IL-6 levels. Grosvenorine can be used for the researches of bacterial infection and Gastric ulcer .

HY-N10455

24-Epicastasterone 2 Publications Verification 24-epi-Castasterone	Drug Derivative	Others
24-Epicastasterone (24-epi-Castasterone) is a bioactive brassinosteroid and a ligand of ABCB1 and ABCB19 in Arabidopsis thaliana. 24-Epicastasterone stimulates the ATPase activity of ABCB19 and the ATP hydrolysis activity of ABCB1, which drive the efflux of substances from plant cells. 24-Epicastasterone increases the activities of catalase and guaiacol peroxidase in the roots of wheat seedlings. 24-Epicastasterone alleviates heat-induced lipid peroxidation through a ROS-dependent mechanism and enhances the heat tolerance of common wheat seedlings .

HY-B0230

Phenylbutazone 3 Publications Verification	COX	Inflammation/Immunology
Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research .

HY-132188

Manganese peroxidase	Endogenous Metabolite	Others
Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .

HY-D1837

Vari Fluor 488 TSA（200×） 2 Publications Verification VF 488 Tyramide	Fluorescent Dye	Others
Vari Fluor 488 TSA（200×） (VF 488 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D0233

Leucocrystal violet	Fluorescent Dye	Others
Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials .

HY-126061

1,7-Dimethyluric acid	Biochemical Assay Reagents Drug Metabolite	Others
1,7-Dimethyluric acid is an N-methylated uric acid and purine derivative, as well as a caffeine metabolite. When 1,7-Dimethyluric acid is acted upon by peroxidase in the presence of H₂O₂, it follows the same oxidation pathway to generate a UV-absorbing intermediate, which decays via first-order kinetics. 1,7-Dimethyluric acid can adsorb onto pyrolytic graphite electrodes, but not onto glassy carbon electrodes or platinum electrodes. The N-methylation modification of its pyrimidine ring prevents ring contraction of the diol intermediate, and no NMR evidence of O-alkylation is observed during propylation under the test conditions .

HY-W000357

4-(Imidazol-1-yl)phenol	Biochemical Assay Reagents	Others
4-(Imidazol-1-yl)phenol is a highly potent signal enhancer in a horseradish peroxidase (HRP)-luminol chemiluminescence (CL) immunoassay .

HY-136247

Cyanine 5 Tyramide Tyramide-Cy5	DNA Stain	Others
Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-136248

Cyanine 3 Tyramide 1 Publications Verification Tyramide-Cy3	DNA Stain Fluorescent Dye	Others
Cyanine 3 Tyramide (Tyramide-Cy3) is an orange fluorescent dye used as a reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition, which serves as a signal amplification technique in immunoassays and in situ nucleic acid hybridization .

HY-B0329S

Isoniazid-d4 INH-d₄; Isonicotinic acid hydrazide-d₄; Isonicotinic hydrazide-d₄	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .

HY-139915

MPO-IN-1	Glutathione Peroxidase	Inflammation/Immunology
MPO-IN-1 is a potent, orally active, and irreversible indole-containing inhibitor of myeloperoxidase (MPO). MPO-IN-1 has IC₅₀s of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively. MPO-IN-1 inhibits MPO activity in an acute mouse model of inflammation .

HY-W013754

S-Hexylglutathione	Glutathione S-transferase	Others
S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase .

HY-W043748

2,5-Dioxopyrrolidin-1-yl acrylate N-Succinimidyl acrylate	Biochemical Assay Reagents	Others
2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues .

HY-W105101

3,5-Dibromotyrosine	Endogenous Metabolite	Others
3,5-Dibromotyrosine is a product of protein oxidation by eosinophil peroxidase .

HY-145197

MPO-IN-3	Glutathione Peroxidase	Cardiovascular Disease
MPO-IN-3 is a potent myeloperoxidase (MPO) inhibitor (WO2013068875A1, example 191). Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the peroxidase superfamily .

HY-139381

MitoEbselen-2 chloride Mitoperoxidase 2	Apoptosis	Metabolic Disease
MitoEbselen-2 chloride (MitoPeroxidase 2), a mitochondria-targeted mimic of glutathione peroxidase, is a radiation mitigator. MitoEbselen-2 chloride is effective in reducing lipid hydroperoxides, preventing apoptotic cell death .

HY-D1835

Vari Fluor 594 TSA (200×) VF 594 Tyramide	Fluorescent Dye	Others
Vari Fluor 594 TSA (200×) (VF 594 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-W614753

Biotin-naphthylamine	Biochemical Assay Reagents	Others
Biotin-naphthylamine is a biotinylated biochemical assay reagent, which is a substrate for *ascorbate peroxidase* 2 (APEX2**). Biotin-naphthylamine is utilized as a novel probe for labeling DNA and RNA .

HY-112841

PTZ-343 3-(10′-Phenothiazinyl)propane-1-sulfonate sodium; SPTZ sodium	Fluorescent Dye	Cancer
PTZ-343 is a potent enhancer of Luminol (HY-15922). PTZ-343 greatly increases the light output of the peroxidase-catalyzed luminol chemiluminescent oxidation reaction (>80%) .

HY-155639

Tyramide alkyne 1 Publications Verification	Biochemical Assay Reagents	Others
Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling .

HY-B0329R

Isoniazid (Standard) INH (Standard); Isonicotinic acid hydrazide (Standard); Isonicotinic hydrazide (Standard)	Reference Standards Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid (Standard) is the analytical standard of Isoniazid. This product is intended for research and analytical applications. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .

HY-D125859F

Peroxidase, Horseradish, Biotin labeled HRP-Biotin	Biochemical Assay Reagents	Others
Peroxidase, Horseradish, Biotin labeled (HRP-Biotin) can be used to encapsulate DNA nanoflowers for creating stabilized streamlined ELISA platforms resistant to harsh environment .

HY-W007967

4-Chloro-1-naphthol	Biochemical Assay Reagents	Others
4-Chloronaphthalen-1-ol is a substrate of horseradish peroxidase. 4-Chloronaphthalen-1-ol can be used to visualize protein bands in western blotting and immunohistochemical staining .

HY-D1831

Vari Fluor 620 TSA (200×) VF 620 Tyramide	Fluorescent Dye	Others
Vari Fluor 620 TSA (200×) (VF 620 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1832

Vari Fluor 532 TSA (200×) VF 532 Tyramide	Fluorescent Dye	Others
Vari Fluor 532 TSA (200×) (VF 532 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1833

Vari Fluor 680 TSA (200×) VF 680 Tyramide	Fluorescent Dye	Others
Vari Fluor 680 TSA (200×) (VF 680 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

Cat. No.	Product Name

HY-L051

Ferroptosis Compound Library

1,177 compounds

Ferroptosis is a novel type of cell death program that is distinct from apoptosis, necroptosis and autophagy. It is dependent on iron and reactive oxygen species (ROS) and is characterized by lipid peroxidation. As a novel type of cell death, ferroptosis has distinct properties and recognizing functions involved in physical conditions or various diseases including cancers, neurodegenerative diseases, acute renal failure, etc.

MCE carefully collected a unique collection of 1,177 ferroptosis signaling pathway related compounds with ferroptosis-inducing or -inhibitory activity. MCE Ferroptosis Compound Library is a useful tool to study ferroptosis mechanism as well as related diseases.

Cat. No.	Product Name	Type

HY-15902

ABTS diammonium salt Maximum Cited Publications 13 Publications Verification AzBTS-(NH4)2	Fluorescent Dye
ABTS diammonium salt (AzBTS-(NH4)2) is a substrate for horseradish peroxidase (HRP) conjugate. ABTS diammonium salt can be used to evaluate antioxidant capacity .

HY-101880

ADHP 2 Publications Verification 10-Acetyl-3,7-dihydroxyphenoxazine	Fluorescent Dye
ADHP is a fluorogenic peroxidase substrate (λ_ex=530 nm, λ_em=590 nm).

HY-D1840

Tyramide Amplification Buffer

1 Publications Verification

Fluorescent Dye

Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). Tyramide Amplification Buffer enables the reaction between tyramide-labeled antibodies and fluorescently labeled tyramide substitutes (tyramide) using peroxidase, resulting in a highly amplified fluorescent signal. Tyramide Amplification Buffer can be used for signal enhancement in detection methods such as immunofluorescence (IF), immunohistochemistry (IHC), or in situ hybridization (FISH) .

HY-15930

TMB

5+ Cited Publications

BM blue; Sure Blue TMB

Fluorescent Dye

TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-15914

DHBS DCHBS	Fluorescent Dye
DHBS (3, 5-dichloro-2-hydroxybenzenesulfonate) is used in conjunction with 4-aminoantipyrine (4-AAP) (HY-W100990) and hydrogen peroxide (H₂O₂) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems .

HY-D2468

HRP-Streptavidin

1 Publications Verification

Fluorescent Dye

Sulfonylurea Receptor HRP-Streptavidin is a biotin-binding signal amplifier designed to bind tightly with biotinylated anti-TSH monoclonal antibodies, thereby constituting a key component of the signal amplification system in immunoassays. HRP-Streptavidin is formed by the covalent coupling of Horseradish Peroxidase (HRP) with Streptavidin; it combines the highly efficient catalytic activity of the enzyme with the high affinity of Streptavidin for biotin, making it a potent and sensitive tool for signal amplification. HRP-Streptavidin is suitable for use in Western Blotting, ELISA, and other detection techniques .

HY-15930A

TMB dihydrochloride

5+ Cited Publications

BM blue dihydrochloride; Sure Blue TMB dihydrochloride

Fluorescent Dye

TMB dihydrochloride is the dihydrochloride form of TMB (HY-15930). TMB dihydrochloride is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB dihydrochloride can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB dihydrochloride can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-D0945

Xylene Cyanol FF

Fluorescent Dye

Xylene Cyanol FF is an acid triphenylmethane dye. Xylene Cyanol FF can be used for histochemical staining of hemoglobin peroxidase or as a tracking dye for DNA sequencing in electrophoresis. Xylene Cyanol FF will be catalyzed by Fe and Al to accelerate oxidation under the addition of double oxidant hydrogen peroxide and potassium periodate. Xylene Cyanol FF thus enables the spectrophotometric determination of Fe and Al in the solution to be tested .

HY-D1837

Vari Fluor 488 TSA（200×） 2 Publications Verification VF 488 Tyramide	Fluorescent Dye
Vari Fluor 488 TSA（200×） (VF 488 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D0233

Leucocrystal violet

Fluorescent Dye

Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials .

HY-136247

Cyanine 5 Tyramide Tyramide-Cy5	Fluorescent Dye
Cyanine 5 Tyramide (Tyramide-Cy5), a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-136248

Cyanine 3 Tyramide 1 Publications Verification Tyramide-Cy3	Fluorescent Dye
Cyanine 3 Tyramide (Tyramide-Cy3) is an orange fluorescent dye used as a reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition, which serves as a signal amplification technique in immunoassays and in situ nucleic acid hybridization .

HY-D2875

5-FITC tyramide 1 Publications Verification	Fluorescent Dye
5-FITC tyramide is a green fluorescent dye composed of FITC (HY-66019) and tyramide (Ex=488 nm, Em=525 nm). 5-FITC tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC) .

HY-D1835

Vari Fluor 594 TSA (200×) VF 594 Tyramide	Fluorescent Dye
Vari Fluor 594 TSA (200×) (VF 594 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D2874

6-AF488 tyramide	Fluorescent Dye
6-AF488 tyramide is a bright, green fluorescent dye (Ex=496 nm, Em=524 nm). 6-AF488 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-FITC tyramide can be used for multiplex immunohistochemistry (mIHC) .

HY-D2872

5-AF594 tyramide	Fluorescent Dye
5-AF594 tyramide is a red fluorescent dye (Ex=590 nm, Em=618 nm). 5-AF594 tyramide is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). 5-AF594 tyramide can be used for multiplex immunohistochemistry (mIHC) .

HY-D1836

Vari Fluor 555 TSA (200x) 1 Publications Verification VF 555 Tyramide	Fluorescent Dye
Vari Fluor 555 TSA (200x) , also know as VF 555 Tyramide. Vari Fluor 555 TSA (200x) is one of Vari Fluor TSA series fluorescent probes, which can be used for high-density in situ labeling assays. Vari Fluor TSA series target antigens via horseradish peroxidase (HRP), which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D125859F

Peroxidase, Horseradish, Biotin labeled HRP-Biotin	Fluorescent Dye
Peroxidase, Horseradish, Biotin labeled (HRP-Biotin) can be used to encapsulate DNA nanoflowers for creating stabilized streamlined ELISA platforms resistant to harsh environment .

HY-D1831

Vari Fluor 620 TSA (200×) VF 620 Tyramide	Fluorescent Dye
Vari Fluor 620 TSA (200×) (VF 620 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1832

Vari Fluor 532 TSA (200×) VF 532 Tyramide	Fluorescent Dye
Vari Fluor 532 TSA (200×) (VF 532 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1833

Vari Fluor 680 TSA (200×) VF 680 Tyramide	Fluorescent Dye
Vari Fluor 680 TSA (200×) (VF 680 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1834

Vari Fluor 640 TSA（200×） 1 Publications Verification VF 640 Tyramide	Fluorescent Dye
Vari Fluor 640 TSA（200×） (VF 640 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D2205

Cy7 tyramide Cy7 TSA	Fluorescent Dye
Cy7 tyramide, a red fluorescent dye, is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids.

HY-D2873

Sulfo Cy7 tyramide Sulfo Cy7(Et) tyramide	Fluorescent Dye
Sulfo Cy7 tyramide, a red fluorescent dye (Ex=740 nm, Em=770 nm), is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). Sulfo Cy7 tyramide can be used for multiplex Immunohistochemistry (mIHC) .

HY-15930C

TMB monosulfate

5+ Cited Publications

BM blue monosulfate; Sure Blue TMB monosulfate

Fluorescent Dye

TMB monosulfate is the monosulfate form of TMB (HY-15930). TMB monosulfate is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB monosulfate can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB monosulfate can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-15930R

TMB (Standard)

BM blue (Standard); Sure Blue TMB (Standard)

Fluorescent Dye

TMB (Standard) is the analytical standard of TMB. This product is intended for research and analytical applications. TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-W411361

Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone PCNPH	Fluorescent Dye
Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone (PCNPH) is a chromogenic substrate to peroxidase enzymes. Pyridine-2-carboxaldehyde 4-nitrophenylhydrazone can form a purple indamine dye with peroxidase enzymes and peroxides .

HY-D1838

Vari Fluor 350 TSA（200×） VF 350 Tyramide	Fluorescent Dye
Vari Fluor 350 TSA（200×） (VF 350 Tyramide) is a fluorescent probe belonging to the Vari Fluor TSA series. Vari Fluor TSA series fluorescent probes can be used for high-density in situ labeling of target antigens using horseradish peroxidase (HRP) assays, which are widely used in ELISA, IF, IHC and other techniques with high detection sensitivity .

HY-D1740

Dihydrotetramethylrosamine DHTM Ros	Fluorescent Dye
Dihydrotetramethylrosamine (DHTM Ros) is a fluorogenic substrate for peroxidase that oxidizes to fluorescent tetramethylrosamine chloride.

HY-120512

5-Phenyl-4E-pentenol

Fluorescent Dye

5-Phenyl-4E-pentenol is a product of the peroxidase-catalyzed reduction of PPHP. 5-Phenyl-4E-pentenol can be rapidly isolated by solid phase extraction and quantified by isocratic reversed-phase high performance liquid chromatography (HPLC) with UV detection. 5-Phenyl-4E-pentenol is a fluorescent dye that can be used to determine the kinetic properties of heme-containing and non-heme peroxidases and to evaluate the ability of oxidative compounds to serve as substrates for peroxidase reduction. .

HY-136248A

Cyanine 3 Tyramide methyl indole	Fluorescent Dye
Cyanine 3 Tyramide methyl indole is a derivative of Cyanine 3 Tyramide (HY-136248). Cyanine 3 Tyramide is an orange fluorescent dye, and is utilized as reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition that is signal amplification technique in immunoassay and in situ hybridization of nucleic acids .

HY-D0233R

Leucocrystal violet (Standard)

Fluorescent Dye

Leucocrystal violet (Standard) is the analytical standard of Leucocrystal violet (HY-D0233). This product is intended for research and analytical applications. Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials.

HY-D1839

Biotin TSA（200×） Biotin Tyramide	Fluorescent Dye
Biotin TSA (200×) (Biotin Tyramide) is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

HY-101880R

ADHP (Standard) 10-Acetyl-3,7-dihydroxyphenoxazine (Standard)	Fluorescent Dye
ADHP (Standard) is the analytical standard of ADHP (HY-101880). This product is intended for research and analytical applications. ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).

Cat. No.	Product Name	Type

HY-125859

Peroxidase, Horseradish 1 Publications Verification	Biochemical Assay Reagents
Peroxidase, Horseradish actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases .

HY-Y0669

Pipecolic acid

2 Publications Verification

Biochemical Assay Reagents

Pipecolic acid is an orally bioavailable, blood-brain barrier-permeable metabolite of lysine with antioxidant, inhibitor, and inducer activity. Pipecolic acid modulates the YAP-GPX4 signaling pathway, reduces retinal vascular tube formation, and mitigates ferroptosis. Pipecolic acid potentiates voltage-sensitive Ca ²⁺ channel currents and induces neuronal apoptosis. Pipecolic acid can be used for the research of diabetic retinopathy .

HY-N0729D

Linoleic acid,suitable for cell culture

Biochemical Assay Reagents

Linoleic acid is a critical component of polyunsaturated fatty acids. Linoleic acid reduces GSH-PX and T-SOD activities. Linoleic acid functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid can cause acute oxidative damage to red blood cells, ultimately leading to partial acute anemia. Linoleic acid can be used in the research of skin diseases associated with linoleic acid deficiency .

HY-B2235C

L-α-Lecithin (soybean)	Biochemical Assay Reagents
L-α-Lecithin (soybean) is an orally active phospholipid. L-α-Lecithin (soybean) increases the bioavailability of Lutein in plasma and eyes of Rattus norvegicus, enhances plasma Glutathione peroxidase activity, and regulates fatty acids in plasma and tissues .

HY-D0945

Xylene Cyanol FF

Biochemical Assay Reagents

HY-W000357

4-(Imidazol-1-yl)phenol	Biochemical Assay Reagents
4-(Imidazol-1-yl)phenol is a highly potent signal enhancer in a horseradish peroxidase (HRP)-luminol chemiluminescence (CL) immunoassay .

HY-15930B

TMB dihydrochloride x.hydrate

Maximum Cited Publications

6 Publications Verification

Sure Blue TMB dihydrochloride x.hydrate

Biochemical Assay Reagents

TMB (dihydrochloride x.hydrate) is the dihydrochloride x hydrate form of TMB (HY-15930). TMB (dihydrochloride x.hydrate) is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB (dihydrochloride x.hydrate) can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB (dihydrochloride x.hydrate) can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-W115789

Sodium silicate

Biochemical Assay Reagents

Sodium silicate is a water-soluble silicate. Sodium silicate is widely used as a binder, particularly in the production of detergents, soaps, and cleaners. Sodium silicate promotes the deposition of suberin polyphenols and lignin at wound sites of potato tubers, accelerates callus structure formation, enhances ROS production, and induces the synthesis of total phenols and flavonoids. Sodium silicate reduces the weight loss rate and disease index of wounded potato tubers during storage .

HY-NP037

Avidin-HRP	Biochemical Assay Reagents
Avidin-HRP is Horseradish Peroxidase (HRP) Avidin. Avidin has excellent affinity with biotin and is often used in combination with biotin for immunoassays to detect the location of antigens in tissues .

HY-W614753

Biotin-naphthylamine	Biochemical Assay Reagents
Biotin-naphthylamine is a biotinylated biochemical assay reagent, which is a substrate for *ascorbate peroxidase* 2 (APEX2**). Biotin-naphthylamine is utilized as a novel probe for labeling DNA and RNA .

HY-NP0152

*Wheat Germ Agglutinin (Peroxidase)* WGA (peroxidase)	Biochemical Assay Reagents
Wheat Germ Agglutinin (WGA) Peroxidase is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Wheat Germ Agglutinin (WGA) Peroxidase is a biological material or organic compound that can be used in life science research .

HY-NP090A

*Ulex Europaeus Agglutinin I (peroxidase)* UEA I (peroxidase)	Biochemical Assay Reagents
Ulex Europaeus Agglutinin I (peroxidase) (UEA I (peroxidase)) has anti-H blood group specificity. Ulex Europaeus Agglutinin I (peroxidase) has an affinity for L-fucose .

HY-NP033

Bovine Serum Albumin-HRP BSA-HRP	Biochemical Assay Reagents
Bovine Serum Albumin-HRP (BSA-HRP) is Horseradish Peroxidase (HRP)-labeled Bovine Serum Albumin (BSA, HY-D0842) .

HY-W013758

TMB-PS sodium TMBZ-PS sodium	Biochemical Assay Reagents
TMB-PS (TMBZ-PS) sodium is a chromogenic substrate for the detection and quantification of peroxidase activity .

Cat. No.	Product Name

HY-K1107

*DAB Peroxidase* Substrate Kit (Purple-Blue Color)**
MCE DAB Peroxidase Substrate Kit (Purple-Blue Color) can be used for staining and color development detection in experiments such as immunohistochemistry of cells or tissues, in situ hybridization, Western blotting, and for visualizing endogenous HRP in cells or tissues.

HY-K1005

Ultra High Sensitivity ECL Kit 160+ Cited Publications
MCE Ultra High Sensitivity ECL Kit is an ultra-sensitive, luminol-based enhanced chemiluminescent substrate for detecting horseradish peroxidase (HRP) labeled antibodies on western blots. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-KD1004A

Vari Fluor 4-colour Multiple Fluorescent Staining Kit-1 (For all samples)

Multiplex immunohistochemistry is also known as Tyramide Signal Amplification (TSA, Tyramide dignal amplification). It has been used for more than 20 years as an enzymatic assay for high-density in situ labelling of target proteins or nucleic acids by horseradish peroxidase (HRP). The method is based on multiple cis-immunostaining with tyramide signal amplification, which allows the detection of multiple target sites in cell or tissue samples in situ, and elucidation of their interaction mechanism through the study of the combination and positional relationship of these target sites.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-112540B

Acetoacetic acid sodium	Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid sodium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid sodium can be used to study metabolic diseases .

HY-B1000A

L-SelenoMethionine 5 Publications Verification	Microorganisms other families Animals Classification of Application Fields Ketones, Aldehydes, Acids Plants Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite Apoptosis
L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-112540

Acetoacetic acid 4 Publications Verification	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite
Acetoacetic acid is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid can be used to study metabolic diseases .

HY-B1306

4-Aminohippuric acid 4 Publications Verification p-Aminohippuric acid	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Others
4-Aminohippuric acid (p-Aminohippuric acid) is a coordination ligand for metal ions (such as Cu ²⁺, Fe ³⁺, Hg ²⁺) and a functionalization reagent for nanomaterials. 4-Aminohippuric acid can coordinate with metal ions or modify the surface of materials such as carbon nanotubes and gold nanoparticles through amino and carboxyl groups. 4-Aminohippuric acid can form stable complexes with metal ions or participate in the synthesis of nanomaterials as a reducing agent/stabilizer, enriching metal ions or giving nanoparticles peroxidase-mimicking activity. 4-Aminohippuric acid can be used to construct highly sensitive electrochemical sensors or colorimetric sensors to detect and quantitatively analyze heavy metal ions such as copper, iron, and mercury in environmental water samples and biological samples. 4-Aminohippuric acid may also be a biomarker for attention-deficit/hyperactivity disorder (ADHD) .

HY-W017113

2-Mercaptobenzothiazole 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR) , inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity . 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1 . 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC₅₀ value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis . 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats . 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes .

HY-N0859

Schisanhenol Schizanhenol; Gomisin-K3	Structural Classification Monophenols Classification of Application Fields Lignans Phenols Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Source Classification Cancer	UGT Cholinesterase (ChE) Tau Protein SOD Sirtuin
Schisanhenol (Schizanhenol), a lignan, is an orally active antioxidant. Schisanhenol reduces AChE activity, increases SIRT1 and PGC-1α expression, and decreases phosphorylated Tau (Ser 396) levels. Schisanhenol increases SOD and glutathione peroxidase activity, decreases malondialdehyde (MDA) content, and inhibits UGT2B7 activitY. Schisanhenol attenuates ox-LDL-induced apoptosis, intracellular reactive oxygen species generation, and cytotoxicity in endothelial cells. Schisanhenol inhibits LDL oxidation, brain mitochondrial and membrane peroxidative damage, and brain mitochondrial swelling and disintegration. Schisanhenol can be used for the research of Alzheimer’s disease, atherosclerosis, brain ischemia, and age-related brain deterioration .

HY-112540A

Acetoacetic acid lithium 4 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Acetoacetic acid lithium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid lithium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid lithium can be used to study metabolic diseases .

HY-N0864

Macranthoidin B Macranthoiside I	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification Cancer	Apoptosis COX Reactive Oxygen Species (ROS) Caspase SOD
Macranthoidin B (Macranthoiside I) is an orally active triterpene saponin. Macranthoidin B inhibits epithelial-mesenchymal transition in endometriosis via the COX‑2/PGE2 pathway, and also induces tumor cell apoptosis and inhibits their proliferation by regulating metabolism and increasing ROS levels . Macranthoidin B can be used in studies related to endometriosis, colorectal cancer and hepatocellular carcinoma .

HY-107858

Veratryl alcohol 1 Publications Verification 3,4-Dimethoxybenzyl alcohol	Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields	Endogenous Metabolite Bacterial
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H₂O₂ and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .

HY-N3031

Grosvenorine	Infection Flavonols Structural Classification Flavonoids Classification of Application Fields Cucurbitaceae Phenols Polyphenols Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Source Classification	Bacterial Apoptosis Bcl-2 Family MDM-2/p53 Glutathione Peroxidase SOD TNF Receptor Interleukin Related
Grosvenorine is an orally active flavonoid glycoside found in S. grosvenorii. Grosvenorine exhibits antibacterial, antioxidant and antiinflammation activities. Grosvenorine can induce apoptosis and increases anti-apoptotic Bcl-2 protein expression and reduces pro-apoptotic P53 protein expression in gastric tissues. Grosvenorine enhances mucin/glycoprotein secretion, regulates gastric pH, and reduces gastric lesion incidence.Grosvenorine increases glutathione peroxidase, catalase, and SOD levels, reduces lipid peroxidation (MDA), and lowers TNF-α and IL-6 levels. Grosvenorine can be used for the researches of bacterial infection and Gastric ulcer .

HY-N10455

24-Epicastasterone 2 Publications Verification 24-epi-Castasterone	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Brassinolide Phytohormone Disease Research Fields Source Classification Agricultural Research	Drug Derivative
24-Epicastasterone (24-epi-Castasterone) is a bioactive brassinosteroid and a ligand of ABCB1 and ABCB19 in Arabidopsis thaliana. 24-Epicastasterone stimulates the ATPase activity of ABCB19 and the ATP hydrolysis activity of ABCB1, which drive the efflux of substances from plant cells. 24-Epicastasterone increases the activities of catalase and guaiacol peroxidase in the roots of wheat seedlings. 24-Epicastasterone alleviates heat-induced lipid peroxidation through a ROS-dependent mechanism and enhances the heat tolerance of common wheat seedlings .

HY-N11849

Moracin N 2 Publications Verification	Phenols Polyphenols Morus alba L. Plants Moraceae Source Classification	Ferroptosis Glutathione Peroxidase
Moracin N is a ferroptosis inhibitor that can be isolated from mulberry leaf. Moracin N exerts neuroprotective activity through preventing from oxidative stress .

HY-132188

Manganese peroxidase	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .

HY-126061

1,7-Dimethyluric acid	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Neurological Disease Classification of Application Fields Disease markers Endogenous metabolite Disease Research Fields Source Classification	Biochemical Assay Reagents Drug Metabolite
1,7-Dimethyluric acid is an N-methylated uric acid and purine derivative, as well as a caffeine metabolite. When 1,7-Dimethyluric acid is acted upon by peroxidase in the presence of H₂O₂, it follows the same oxidation pathway to generate a UV-absorbing intermediate, which decays via first-order kinetics. 1,7-Dimethyluric acid can adsorb onto pyrolytic graphite electrodes, but not onto glassy carbon electrodes or platinum electrodes. The N-methylation modification of its pyrimidine ring prevents ring contraction of the diol intermediate, and no NMR evidence of O-alkylation is observed during propylation under the test conditions .

HY-N6937

(R,R)-Secoisolariciresinol diglucoside 1 Publications Verification (R,R)-SDG; (R,R)-LGM2605	Linum usitatissimum Linn. Classification of Application Fields Linaceae Lignans Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Others
(R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .

HY-149132

Dendrogenin A DDA	Triterpenes Terpenoids Endogenous metabolite Source Classification	LXR
Dendrogenin A (DDA) is a ligand for liver X receptor (LXR), that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC₅₀ of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase .

HY-B1000AR

L-SelenoMethionine (Standard)	Structural Classification Microorganisms other families Animals Ketones, Aldehydes, Acids Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Apoptosis
L-SelenoMethionine (Standard) is the analytical standard of L-SelenoMethionine. This product is intended for research and analytical applications. L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase .

HY-N3027

Soyasaponin Aa 1 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Leguminosae Glycine max (L.) merr Terpenoids Metabolic Disease Plants Disease Research Fields Source Classification	PPAR Reactive Oxygen Species (ROS)
Soyasaponin Aa is a soyasaponin that can be found in soy. Soyasaponin Aa suppresses PPARγ transcriptional activity, reduces PPARγ and C/EBPα expression, inhibits adipocyte differentiation and lipid accumulation, and reduces adipogenic marker gene expression. Soyasaponin Aa reduces hydrogen peroxide-induced reactive oxygen species (ROS) production and malondialdehyde levels. Soyasaponin Aa exhibits cellular antioxidant activity. Soyasaponin Aa can be used for the research of obesity .

HY-B1306R

4-Aminohippuric acid (Standard) p-Aminohippuric acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Biochemical Assay Reagents
4-Aminohippuric acid (p-Aminohippuric acid) (Standard) is the analytical standard of 4-Aminohippuric acid (HY-B1306). This product is intended for research and analytical applications. 4-Aminohippuric acid (p-Aminohippuric acid) is a coordination ligand for metal ions (such as Cu ²⁺, Fe ³⁺, Hg ²⁺) and a functionalization reagent for nanomaterials. 4-Aminohippuric acid can coordinate with metal ions or modify the surface of materials such as carbon nanotubes and gold nanoparticles through amino and carboxyl groups. 4-Aminohippuric acid can form stable complexes with metal ions or participate in the synthesis of nanomaterials as a reducing agent/stabilizer, enriching metal ions or giving nanoparticles peroxidase-mimicking activity. 4-Aminohippuric acid can be used to construct highly sensitive electrochemical sensors or colorimetric sensors to detect and quantitatively analyze heavy metal ions such as copper, iron, and mercury in environmental water samples and biological samples. 4-Aminohippuric acid may also be a biomarker for attention-deficit/hyperactivity disorder (ADHD) .

HY-132183

Chloride peroxidase	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Chloride peroxidase is a monomeric, heme-containing enzyme. Chloride peroxidase is capable of electrophilic chlorinations through the umpolung of chloride by oxidation with hydrogen peroxide .

HY-N0224A

Goitrin (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone	Natural Products Cruciferous vegetables Classification of Application Fields Metabolic Disease Plants Brassicaceae Endogenous metabolite Disease Research Fields Source Classification	Influenza Virus
Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .

HY-N16658

Asperilin NSC 85238	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Oparanthus teikiteetinii (J.Florence & Stuessy) R.K.Shannon & W.L.Wagner Source Classification	Glutathione Peroxidase
Asperilin (NSC 85238) is an orally active sesquiterpene lactone. Asperilin is an effective hydroxyl radical scavenger. Asperilin significantly enhance the lipid peroxidation levels of liver microsomes in various systems. Asperilin leads to a significant decrease in liver glutathione (GSH) levels and an increase in glutathione peroxidase (GPx) activity. Asperilin can be used for research on inflammatory conditions .

HY-N9097

Niazirin	Structural Classification Moringa oleifera Lam. Moringaceae Plants Saccharides Monosaccharides Source Classification	Reactive Oxygen Species (ROS) SOD Glutathione Peroxidase PKC NADPH Oxidase
Niazirin is an orally active antioxidant. Niazirin can be isolated from Moringa oleifera Lam. Niazirin reduces the production levels of ROS and MDA, while increasing the levels of superoxide dismutase SOD and glutathione peroxidase GPx. Niazirin also abolishes high glucose-induced PKCζ activation and inhibits Nox4 protein expression. Niazirin exhibits excellent free radical scavenging activity. Niazirin significantly inhibits high glucose-induced proliferation of vascular smooth muscle cells. Niazirin can be used in the research of diabetic atherosclerosis .

HY-N9928

Echinenone	Animals Ketones, Aldehydes, Acids Source Classification	Cholinesterase (ChE)
Echinenone is an acetylcholinesterase (AChE) inhibitor (IC₅₀=16.29 μg/mL) with anti-Aβ(25-35) activity. Echinenone can inhibit MDA content and increase superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities to cope with oxidative stress damage .

HY-155852

Lepadin H	Structural Classification Alkaloids Animals Marine natural products Other marine organisms Quinoline Alkaloids Source Classification	Ferroptosis Apoptosis ACSL Family Glutathione Peroxidase Reactive Oxygen Species (ROS)
Lepadin H is a ferroptosis inducer and apoptosis inducer with in vitro cytotoxicity and in vivo antitumor efficacy against cancer cells. Lepadin H reduces GPX4 and SLC7A11 levels, increases p53 and ACSL4 expression, drives lipid hydroperoxide production, elevates reactive oxygen species (ROS) levels, reduces cellular glutathione (GSH) levels, induces lipid peroxidation and G₂/M phase cell cycle arrest, and suppresses clonogenic growth and migration of cancer cells.Lepadin H can be used for the research of melanoma .

HY-N6937R

(R,R)-Secoisolariciresinol diglucoside (Standard) (R,R)-SDG (Standard); (R,R)-LGM2605 (Standard)	Structural Classification Linum usitatissimum Linn. Linaceae Lignans Phenylpropanoids Plants Source Classification	Reference Standards Others
(R,R)-Secoisolariciresinol diglucoside (Standard) is the analytical standard of (R,R)-Secoisolariciresinol diglucoside. This product is intended for research and analytical applications. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .

HY-112540AR

Acetoacetic acid lithium (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Acetoacetic acid (lithium) (Standard) is the analytical standard of Acetoacetic acid (lithium). This product is intended for research and analytical applications. Acetoacetic acid lithium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid lithium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid lithium can be used to study metabolic diseases .

HY-N3031R

Grosvenorine (Standard)	Flavonols Structural Classification Flavonoids Cucurbitaceae Phenols Polyphenols Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Source Classification	Reference Standards Bacterial Apoptosis Bcl-2 Family MDM-2/p53 Glutathione Peroxidase SOD TNF Receptor Interleukin Related
Grosvenorine (Standard) is the analytical standard of Grosvenorine. This product is intended for research and analytical applications. Grosvenorine is an orally active flavonoid glycoside found in S. grosvenorii. Grosvenorine exhibits antibacterial, antioxidant and antiinflammation activities. Grosvenorine can induce apoptosis and increases anti-apoptotic Bcl-2 protein expression and reduces pro-apoptotic P53 protein expression in gastric tissues. Grosvenorine enhances mucin/glycoprotein secretion, regulates gastric pH, and reduces gastric lesion incidence.Grosvenorine increases glutathione peroxidase, catalase, and SOD levels, reduces lipid peroxidation (MDA), and lowers TNF-α and IL-6 levels. Grosvenorine can be used for the researches of bacterial infection and Gastric ulcer .

HY-N0859R

Schisanhenol (Standard) Schizanhenol (Standard); Gomisin-K3 (Standard)	Structural Classification Monophenols Lignans Phenols Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Source Classification	UGT Reference Standards Cholinesterase (ChE) Tau Protein SOD Sirtuin
Schisanhenol (Standard) (Schizanhenol (Standard)) is the analytical standard of Schisanhenol (HY-N0859). This product is intended for research and analytical applications. Schisanhenol, a lignan, is an orally active antioxidant. Schisanhenol reduces AChE activity, increases SIRT1 and PGC-1α expression, and decreases phosphorylated Tau (Ser 396) levels. Schisanhenol increases SOD and glutathione peroxidase activity, decreases malondialdehyde (MDA) content, and inhibits UGT2B7 activitY. Schisanhenol attenuates ox-LDL-induced apoptosis, intracellular reactive oxygen species generation, and cytotoxicity in endothelial cells. Schisanhenol inhibits LDL oxidation, brain mitochondrial and membrane peroxidative damage, and brain mitochondrial swelling and disintegration. Schisanhenol can be used for the research of Alzheimer’s disease, atherosclerosis, brain ischemia, and age-related brain deterioration.

HY-N13756

Deoxymikanolide	Structural Classification Terpenoids Sesquiterpenes Asteraceae Mikania micrantha Kunth Plants Source Classification	Bacterial Reactive Oxygen Species (ROS) SOD
Deoxymikanolide is an orally active antibacterial agent that inhibits catalase (CAT), *peroxidase* (POD), and superoxide dismutase (SOD) activities. Deoxymikanolide increases glycan metabolism, phosphorus metabolism, electric conductivity, intrabacterial reactive oxygen species (ROS) levels, and malondialdehyde (MDA) levels, causes cell shrinkage, cytoplasmic damage, and cell disruption in Ralstonia solanacearum. Deoxymikanolide inhibits Acetic acid-induced writhing in mice. Deoxymikanolide can be used for the research of bacterial wilt .

Species:	Human (10) Mouse (1) Pig (2)
Tag:	His (11) Myc (2) Fc (1) Flag (1)
Source:	HEK293 (4) Sf9 insect cells (1) P. pastoris (1) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703942

	GPX4 Protein, Human (U73C, HEK293, Flag) Phospholipid hydroperoxide glutathione peroxidase; PHGPx; Glutathione peroxidase 4; GPx-4; GSHPx-4	Human	HEK293
	GPX4 Protein, Human (U73C, HEK293, Flag) is the recombinant human-derived GPX4 protein, expressed by HEK293, with N-Flag tag.

HY-P72211

	EGLP/GPX5 Protein, Pig (His-Myc) GPX5Epididymal secretory glutathione peroxidase; EC 1.11.1.9; Epididymis-specific glutathione peroxidase-like protein; EGLP; Glutathione peroxidase 5; GPx-5; GSHPx-5	Pig	E. coli
	EGLP/GPX5 may constitute a protective system similar to glutathione peroxidase, protecting sperm membrane lipids from peroxidative damage. Despite the limited enzyme activity, the protective effect suggests an effect beyond enzyme function. EGLP/GPX5 Protein, Pig (His-Myc) is the recombinant pig-derived EGLP/GPX5 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.

HY-P71739

	EGLP/GPX5 Protein, Pig (P.pastoris, Myc, His) GPX5; Epididymal secretory glutathione peroxidase; EGLP; Glutathione peroxidase 5; GPx-5; GSHPx-5	Pig	P. pastoris
	EGLP/GPX5 may constitute a protective system similar to glutathione peroxidase, protecting sperm membrane lipids from peroxidative damage. Despite the limited enzyme activity, the protective effect suggests an effect beyond enzyme function. EGLP/GPX5 Protein, Pig (P.pastoris, Myc, His) is the recombinant pig-derived EGLP/GPX5 protein, expressed by P. pastoris , with N-His, C-Myc labeled tag.

HY-P702646

	GPX4 Protein, Human (U73S, His) PHGPx; Glutathione peroxidase 4; GPx-4; GSHPx-4	Human	E. coli
	GPX4 Protein, Human (U73S, His) is the recombinant human-derived GPX4, expressed by E. coli , with N-6*His labeled tag. ,

HY-P73582

	*TPO/Thyroid peroxidase* Protein, Human (A257S, T725P, sf9, His)** Thyroid peroxidase; TPO; THPO	Human	Sf9 insect cells
	Thyroid peroxidase (TPO) plays a pivotal role in iodination and coupling of tyrosines in thyroglobulin, crucial for synthesizing essential thyroid hormones T(3) and T(4). TPO/Thyroid peroxidase Protein, Human (A257S, T725P, sf9, His) is the recombinant human-derived TPO/Thyroid peroxidase protein, expressed by Sf9 insect cells , with C-10*His labeled tag.

HY-P75798

	GPX7 Protein, Human (HEK293, Fc) Glutathione peroxidase 7; GPx-7; GSHPx-7; CL683; GPX6	Human	HEK293
	GPX7, a protein with catalase activity, is predicted to respond to oxidative stress. It is located in the endoplasmic reticulum and is expressed in various tissues, including placenta (RPKM 15.6) and thyroid (RPKM 9.2). This highlights the potential importance of GPX7 in antioxidative processes throughout the body. GPX7 Protein, Human (HEK293, Fc) is the recombinant human-derived GPX7 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P71231

	PRDX1/Peroxiredoxin-1 Protein, Human (His) 2 Publications Verification Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; PAGA; PAGB; TDPX2	Human	E. coli
	Peroxiredoxin-1 (PRDX1) is a thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides and plays a crucial role in cellular protection against oxidative stress. It detoxifies peroxide and senses hydrogen peroxide-mediated signaling events. PRDX1/Peroxiredoxin-1 Protein, Human (His) is the recombinant human-derived PRDX1 protein, expressed by E. coli , with C-6His, N-6His labeled tag.

HY-P78045

	*TPO/Thyroid Peroxidase* Protein, Mouse (HEK293, His)** TPO; thyroidperoxidase; EC 1.11.1.8; EC 1.11.1	Mouse	HEK293
	Thyroid Peroxidase (TPO) orchestrates iodination and coupling within thyroglobulin, leading to the synthesis of thyroid hormones T(3) and T(4).TPO/Thyroid Peroxidase Protein, Mouse (HEK293, His) is the recombinant mouse-derived TPO/Thyroid Peroxidase protein, expressed by HEK293 , with C-His labeled tag.

HY-P71232

	PRDX4 Protein, Human (His) 1 Publications Verification Peroxiredoxin-4; Antioxidant Enzyme AOE372; AOE37-2; Peroxiredoxin IV; Prx-IV; Thioredoxin peroxidase AO372; Thioredoxin-Dependent Peroxide Reductase A0372; PRDX4	Human	E. coli
	PRDX4, a thiol-specific peroxidase, enzymatically reduces hydrogen peroxide and organic hydroperoxides, crucial for cellular protection. It detoxifies peroxides, acts as a sensor for hydrogen peroxide-mediated signaling, and contributes to NF-kappa-B activation regulation. PRDX4's multifaceted activity underscores its significance in cellular redox homeostasis and potential impact on intracellular signaling. PRDX4 Protein, Human (His) is the recombinant human-derived PRDX4 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71464

	Peroxiredoxin-2/PRDX2 Protein, Human (His) Epididymis secretory sperm binding protein Li 2a; HEL S 2a; MGC4104; Natural killer cell enhancing factor B; Natural killer cell-enhancing factor B; Natural Killer Enhancing Factor B; NKEF B; NKEF-B; NKEFB; Peroxiredoxin 2; Peroxiredoxin-2; PRDX 2; PRDX2; PrP; PRX2; PRXII; PTX1; TDPX1; Thiol Specific Antioxidant 1 ; Thiol specific antioxidant protein; Thiol-specific antioxidant protein; Thioredoxin Dependent Peroxide Reductase 1; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1; Torin; TPX1; TSA	Human	E. coli
	Peroxiredoxin-2 (PRDX2) is a thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides, which is essential for cellular protection against oxidative stress. It detoxifies peroxide, senses hydrogen peroxide-mediated signaling events, and may participate in signaling cascades initiated by growth factors and tumor necrosis factor-alpha. Peroxiredoxin-2/PRDX2 Protein, Human (His) is the recombinant human-derived Peroxiredoxin-2/PRDX2 protein, expressed by E. coli , with N-His labeled tag.

HY-P71146

	PRDX5/Peroxiredoxin-5 Protein, Human (HEK293, His) Peroxiredoxin-5; PRDX5; Alu corepressor 1; Antioxidant enzyme B166; AOEB166; Liver tissue 2D-page spot 71B; PLP; Peroxiredoxin V; Prx-V; Peroxisomal antioxidant enzyme; TPx type VI; Thioredoxin peroxidase PMP20; Thioredoxin reductase	Human	HEK293
	The PRDX5 protein (or Peroxiredoxin-5) plays a critical role as a thiol-specific peroxidase that reduces hydrogen peroxide and organic hydroperoxides. This enzyme activity is essential for cells to defend against oxidative stress and detoxify peroxides. PRDX5/Peroxiredoxin-5 Protein, Human (HEK293, His) is the recombinant human-derived PRDX5/Peroxiredoxin-5 protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P705666

	Ceruloplasmin Protein, Human (His) Ceruloplasmin; CP; Ceruloplasmin; Cuproxidase ceruloplasmin (EC:1.16.3.41); Ferroxidase ceruloplasmin (EC:1.16.3.12); EC:1.16.3.1; Glutathione peroxidase ceruloplasmin (EC:1.11.1.92); EC:1.11.1.9; Glutathione-dependent peroxiredoxin ceruloplasmin (EC:1.11.1.27)	Human	E. coli

HY-P71145

	PRDX6 Protein, Human (His) Peroxiredoxin-6; 1-Cys Peroxiredoxin; 1-Cys PRX; 24 kDa Protein; Acidic Calcium-Independent Phospholipase A2; aiPLA2; Antioxidant Protein 2; Liver 2D PAGE Spot 40; Non-Selenium Glutathione peroxidase; NSGPx; Red Blood Cells Page Spot 12; PRDX6; AOP2; KIAA0106	Human	E. coli
	The PRDX6 protein is a thiol-specific peroxidase that plays a crucial role in cellular defense against oxidative stress. It catalyzes the reduction of hydrogen peroxide and various organic hydroperoxides to water and alcohols. PRDX6 Protein, Human (His) is the recombinant human-derived PRDX6 protein, expressed by E. coli , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B0329S

Isoniazid-d4
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity .

HY-B0230S

Phenylbutazone(diphenyl-d10)
Phenylbutazone(diphenyl-d₁₀) is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research .

HY-W015600S

2-Acetamidophenol-d3

2-Acetamidophenol-d₃ (Orthocetamol-d₃) is the deuterium labeled 2-Acetamidophenol (HY-W015600). 2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .

HY-B0230S2

Phenylbutazone-13C12
Phenylbutazone- ¹³C₁₂ is the ¹³C₁₂ labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research.

HY-B1306S

4-Aminohippuric acid-d4

4-Aminohippuric acid-d₄ (p-Aminohippuric acid-d₄) is the deuterium labeled 4-Aminohippuric acid (HY-B1306). 4-Aminohippuric acid (p-Aminohippuric acid) is a coordination ligand for metal ions (such as Cu ²⁺, Fe ³⁺, Hg ²⁺) and a functionalization reagent for nanomaterials. 4-Aminohippuric acid can coordinate with metal ions or modify the surface of materials such as carbon nanotubes and gold nanoparticles through amino and carboxyl groups. 4-Aminohippuric acid can form stable complexes with metal ions or participate in the synthesis of nanomaterials as a reducing agent/stabilizer, enriching metal ions or giving nanoparticles peroxidase-mimicking activity. 4-Aminohippuric acid can be used to construct highly sensitive electrochemical sensors or colorimetric sensors to detect and quantitatively analyze heavy metal ions such as copper, iron, and mercury in environmental water samples and biological samples. 4-Aminohippuric acid may also be a biomarker for attention-deficit/hyperactivity disorder (ADHD) .

HY-W738271

Veratryl alcohol-13C

Veratryl alcohol- ¹³C (3,4-Dimethoxybenzyl alcohol- ¹³C) is the ¹³C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .

HY-W740777

4-Hydroxyphenylbutazone-d9
4-Hydroxyphenylbutazone-d₉ is the deuterium labeled 4-Hydroxyphenylbutazone (HY-139199). 4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory agent (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS) .

HY-D0233S

Leucocrystal violet-d6

Leucocrystal violet-d₆ is the deuterium labeled Leucocrystal violet (HY-D0233). Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials.

HY-B0230S1

Phenylbutazone-d9
Phenylbutazone-d₉ is the deuterium labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research .

HY-W744953

Carbimazole-d3

Carbimazole-d₃ is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .

HY-B0558S

Carbimazole-d5

Carbimazole-d₅ is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .

HY-N6937S1

(R,R)-Secoisolariciresinol diglucoside-d6

(R,R)-Secoisolariciresinol diglucoside-d₆ is deuterated labeled (R,R)-Secoisolariciresinol diglucoside (HY-N6937). (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .

Host:	Mouse (7) Rabbit (12)
Reactivity:	Human (19) Mouse (12) Rat (12)
Application:	IHC-P (16) ICC/IF (13) IP (6) IHC-F (5) WB (17) FC (2) ELISA (4)
Isotype:	IgG (13) IgG1 (3) IgG2b (2)
Conjugation:	Non-conjugated (19)
Clonality:	Polyclonal (2) Monoclonal (14) Recombinant (7)
Modification:	Unmodified (16)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80146

	*Glutathione Peroxidase* 1 Antibody (YA749)**	WB, IHC-P, ICC/IF, FC	Human
	Glutathione Peroxidase 1 Antibody (YA749) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Glutathione Peroxidase 1.

HY-P80410

	*Glutathione Peroxidase* 1 Antibody (YA404)**	WB, ICC/IF, IP	Human, Rat
	Glutathione Peroxidase 1 Antibody (YA404) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glutathione Peroxidase 1.

HY-P87392

	GPX5 Antibody (YA7075) Arep; arMEP24; EGLP; Epididymal androgen related protein; Epididymal secretory glutathione peroxidase; epididymis secretory sperm binding protein Li 75p; Epididymis specific glutathione peroxidase like protein; Epididymis-specific glutathione peroxidase-like protein; Glutathione peroxidase 5; Glutathione peroxidase 5 (epididymal androgen related protein)	WB, ICC/IF, FC	Human, Mouse, Rat
	GPX5 Antibody (YA7075) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GPX5.

HY-P86239

	GPX4 Antibody (YA5931) Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; PHGPx; Glutathione peroxidase 4; GPx-4; GSHPx-4;	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	GPX4 Antibody (YA5931) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GPX4.

HY-P80692

	GPX4 Antibody 4 Publications Verification Phospholipid hydroperoxide glutathione peroxidase; mitochondrial; PHGPx; EC 1.11.1.12; Glutathione peroxidase 4; GPx-4; GSHPx-4	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	GPX4 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to GPX4.

HY-P85971

	*Thyroid Peroxidase* Antibody (YA5663)**	IHC-P, ICC/IF, ELISA	Human
	Thyroid Peroxidase Antibody (YA5663) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Thyroid Peroxidase.

HY-P81194

	EPX Antibody Eosinophil peroxidase; Eosinophil peroxidase heavy chain; EPER; EPO; EPP; EPX PEN; PERE; PERE_HUMAN.	IHC-P, IHC-F, ICC/IF	Human, Mouse
	EPX Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to EPX.

HY-P80692A

	GPX4 Antibody (YA9649)(PBS only) Phospholipid hydroperoxide glutathione peroxidase; mitochondrial; PHGPx; EC 1.11.1.12; Glutathione peroxidase 4; GPx-4; GSHPx-4	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	GPX4 Antibody(YA9649)(PBS only) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GPX4.

HY-P81735

	*Thyroid Peroxidase* Antibody (YA1480)** MSA; TDH2A; TPO; TPX	WB, IHC-P, IP	Human
	Thyroid Peroxidase Antibody (YA1480) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Thyroid Peroxidase.

HY-P82408

	*Glutathione Peroxidase* 2 Antibody (YA2153)** GI GPx; GPRP; GPRP-2; GPx-GI; GPX2; GSHPx 2; GSHPx GI; GSHPx-2; GSHPx-GI	WB, IHC-P	Human
	Glutathione Peroxidase 2 Antibody (YA2153) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Glutathione Peroxidase 2.

HY-P83478

	MGST3 Antibody (YA3223) Glutathione peroxidase MGST3; LTC4 synthase MGST3; Microsomal GST-III	WB, IHC-P, IP	Human
	MGST3 Antibody (YA3223) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MGST3.

HY-P80782

	Peroxiredoxin 1 Antibody (YA692) PRDX1; PAGA; PAGB; TDPX2; Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Peroxiredoxin 1 Antibody (YA692) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Peroxiredoxin 1.

HY-P81840

	Peroxiredoxin 2 Antibody (YA1585) PRDX2; NKEFB; TDPX1; Peroxiredoxin-2; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1	WB, IHC-P	Human, Mouse, Rat
	Peroxiredoxin 2 Antibody (YA1585) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Peroxiredoxin 2.

HY-P85678

	Peroxiredoxin 1 Antibody (YA5370) PRDX1; PAGA; PAGB; TDPX2; Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Peroxiredoxin 1 Antibody (YA5370) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Peroxiredoxin 1.

HY-P86506

	Peroxiredoxin 1 Antibody (YA6198) PRDX1; PAGA; PAGB; TDPX2; Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Peroxiredoxin 1 Antibody (YA6198) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Peroxiredoxin 1.

HY-P80782A

	Peroxiredoxin 1 Antibody (YA692)(PBS only) PRDX1; PAGA; PAGB; TDPX2; Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Peroxiredoxin 1 Antibody (YA692) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Peroxiredoxin 1.

HY-P81840A

	Peroxiredoxin 2 Antibody (YA1585)(PBS only) PRDX2; NKEFB; TDPX1; Peroxiredoxin-2; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1	WB, IHC-P	Human, Mouse, Rat
	Peroxiredoxin 2 Antibody (YA1585) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Peroxiredoxin 2.

HY-P83478A

	MGST3 Antibody (YA3223)(PBS only) Glutathione peroxidase MGST3; LTC4 synthase MGST3; Microsomal GST-III	WB, IHC-P, IP	Human
	MGST3 Antibody (YA3223) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MGST3.

HY-P85882

	MPO Antibody (YA5574) 84 kDa myeloperoxidase antibody; 89 kDa myeloperoxidase antibody; EC1.11.2.2 antibody; fj80f04 antibody; MPO antibody; mpx antibody; myeloid-specific peroxidase antibody; Myeloperoxidase antibody; Myeloperoxidase heavy chain antibody; Myeloperoxidase light chain antibody; PERM_HUMAN antibody; wu:fj80f04 antibody	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	MPO Antibody (YA5574) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to MPO.

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HY-131442

Alkyne-phenol 3 Publications Verification Alkyne tyramide; Alk-Ph		Alkynes Labeling and Fluorescence Imaging
Alkyne-phenol (Alk-Ph) is a clickable *ascorbate peroxidase* 2 (APEX2)** probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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peroxidase

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