2 Results for "

phase I hydroxyl metabolite

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "phase I hydroxyl metabolite" in MCE Product Catalog:

Cat. No.: HY-117580
CAS No.: 13951-70-7
Synonyms: OH-PRED
Target:  

Drug Metabolite

Research Areas:  

Inflammation/Immunology

16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily .
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Cat. No.: HY-N7177
CAS No.: 18887-18-8
Hydroxytanshinone IIA is a hydrolytic metabolite of Tanshinone IIA (HY-N0135). Tanshinone IIA inhibits angiogenesis by targeting the protein kinase domain of VEGF/VEGFR2. Hydroxytanshinone IIA exhibits antioxidant and anti-inflammatory activities. Hydroxytanshinone IIA can be used in studies of angina pectoris and myocardial infarction .
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