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phytoene desaturase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetolactate Synthase (ALS) (1) Apoptosis (1) Biochemical Assay Reagents (1) Calcium Channel (1) Cytochrome P450 (1) Environmental Pollutants (2) Herbicide (6) Isotope-Labeled Compounds (1) p38 MAPK (1) PI3K (1) Reactive Oxygen Species (ROS) (2) Reference Standards (1)
By Research Areas:	Inflammation/Immunology (1)

Inhibitors & Agonists

Isotope-Labeled Compounds

Targets Recommended: Dihydroceramide Desaturase 1 (DES1) Stearoyl-CoA Desaturase (SCD)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W040206

Diflufenican	Environmental Pollutants Acetolactate Synthase (ALS) Herbicide	Others
Diflufenican is a Herbicide. Diflufenican inhibits phytoene desaturase (PDS) in the carotenoid synthesis pathway. Diflufenican suppresses the production of PDS, blocks carotenoid biosynthesis, thereby inducing chlorophyll destruction and cell membrane rupture, and ultimately causes the death of broadleaf weeds. The combination of Diflufenican and Flufenacet can be used to control Lolium rigidum populations resistant to ALS/ACCase .

HY-114849

Norflurazon SAN 9789	Environmental Pollutants Herbicide	Others
Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

HY-151095

Phytoene desaturase-IN-1	Reactive Oxygen Species (ROS)	Others
Phytoene desaturase-IN-1 is a potent phytoene desaturase (PDS) inhibitor (K_d: 65.9 μM) through π−π stacking effect with Phe301 residue. Phytoene desaturase-IN-1 shows broad spectrum of postemergence herbicidal activity. Phytoene desaturase-IN-1 induces PDS mRNA reduction, phytoene and reactive oxygen species (ROS) accumulation in albino leaves. Phytoene desaturase-IN-1 can be used in the area of agricultural production .

HY-157024

Phytoene desaturase-IN-2	Herbicide	Others
PDS-IN-1 is a potent inhibitor of Oryza sativa phytoene desaturase (OsPDS), resulting in herbicidal activity .

HY-114849R

Norflurazon (Standard) SAN 9789 (Standard)	Herbicide Reference Standards	Others
Norflurazon (Standard) is the analytical standard of Norflurazon. This product is intended for research and analytical applications. Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

HY-169011

Phytoene desaturase-IN-3	Herbicide	Others
Phytoene desaturase-IN-3 (compound 8e) is a potent inhibitor of Phytoene desaturase . Phytoene desaturase-IN-3 has herbicidal activity .

HY-W711035

Picolinafen AC 900001	p38 MAPK PI3K Calcium Channel Reactive Oxygen Species (ROS) Apoptosis Cytochrome P450	Inflammation/Immunology
Picolinafen is a pyridine-class herbicide that acts as a phytoene desaturase (PDS) inhibitor. Picolinafen effectively controls broadleaf weeds and disrupts carotenoid biosynthesis. Picolinafen exhibits cytotoxicity to porcine trophectoderm (pTr) and luminal epithelial (pLE) cells. Picolinafen induces (ROS accumulation, calcium depletion, and activates (MAPK and PI3K signaling pathways, leading to decreased cell viability, increased apoptosis, impaired migration, and altered expression of implantation-related genes. Picolinafen has an LD₅₀ value of 2.7 mg/kg in mammals and 7 μg/L in fish. Picolinafen exhibits toxic effects during zebrafish embryogenesis ^[1][2].

HY-E71192

15-cis-Phytoene desaturase	Biochemical Assay Reagents	Others
15-cis-Phytoene desaturase (EC 1.3.5.5) is involved in carotenoid biosynthesis in plants and cyanobacteria.

HY-W778236

Norflurazon-13C,d3 SAN 9789-¹³C,d₃	Isotope-Labeled Compounds Herbicide	Others
Norflurazon- ¹³C,d₃ (SAN 9789- ¹³C,d₃) is the deuterium and ¹³C-labeled Norflurazon (HY-114849). Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

Norflurazon-13C,d3
Norflurazon- ¹³C,d₃ (SAN 9789- ¹³C,d₃) is the deuterium and ¹³C-labeled Norflurazon (HY-114849). Norflurazon (SAN 9789) is a bleaching herbicide. Norflurazon can block carotenoid biosynthesis by inhibiting phytoene desaturase activity .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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