Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
pine wood nematodes
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "pine wood nematodes" in MCE Product Catalog:
1
Cat. No.: HY-N14239
CAS No.: 109766-61-2
Category:
Target:
Cat. No.: HY-N8504
CAS No.: 59795-94-7
Synonyms: NSC 260179; Spectinabilin
Neoaureothin is a bacterial metabolite that has been found in Streptomyces. It is an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs (IC50=13 μM) and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50=1.75 nM). Neoaureothin is cytotoxic to A549, HCT116, and HepG2 cells (IC50s=34.3, 47, and 37.2 μg/mL, respectively). It also has nematocidal activity against the pine wood nematode B. xylophilus (LC50=0.84 μg/mL) and increases survival of P. densiflora trees inoculated with B. xylophilus.
Cat. No.: HY-N3754
CAS No.: 17635-59-5
Category:
Infection Monophenols Pinaceae Pinus pumila (Pall.) Regel Phenols Plants Disease Research Fields
Target:
Cat. No.: HY-171720
CAS No.: 1355681-43-4
Synonyms: Asc-C6
Target:
Research Areas:
Ascr#12 (Asc-C6) is an ascaroside derivative that exhibits extremely low activity in inducing the dauer (dormant larval) stage. Ascr#12 enhances the reproductive capacity of the invasive pine wood nematode .
Cat. No.: HY-187808
CAS No.: 257880-89-0
Target:
Cholinesterase (ChE) Insecticide SOD Glutathione S-transferase Reactive Oxygen Species (ROS)
Research Areas:
Insecticidal agent 38 is a AChE inhibitor and Insecticide, with an IC50 of 49.08 μg/mL against AChE. Insecticidal agent 38 inhibits the activities of SOD, Catalase and Glutathione-S-transferase. Insecticidal agent 38 induces intracellular ROS, lipofuscin and lipid accumulation, increases malondialdehyde levels, disrupts redox homeostasis and triggers oxidative damage. Insecticidal agent 38 inhibits the feeding and reproductive capabilities of the pine wood nematode (Bursaphelenchus xylophilus). Insecticidal agent 38 exhibits insecticidal activity against nematodes. Insecticidal agent 38 can be used in studies of plant-parasitic nematode infections .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
