Ascr#12
Ascr#12 (Asc-C6) is an ascaroside derivative that exhibits extremely low activity in inducing the dauer (dormant larval) stage. Ascr#12 enhances the reproductive capacity of the invasive pine wood nematode.
For research use only. We do not sell to patients.
- CAS No.: 1355681-43-4
- Formula: C12H22O6
- Molecular Weight:262.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
asc-C6 (220-6000 nM) exhibits negligible dauer-inducing activity in Caenorhabditis elegans[1].
Synthetic asc-C6 (3 aM-3 µM; 72 h) increases fecundity of the invasive Bursaphelenchus xylophilus CN1 isolate, but has no significant effect on the US1 isolate[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1355681-43-4
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Molecular Weight 262.30
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Formula C12H22O6
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SMILES
O([C@@H](CCCC(O)=O)C)[C@H]1[C@H](O)C[C@@H](O)[C@H](C)O1
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Synonyms
Asc-C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hollister KA, et al. Ascaroside activity in Caenorhabditis elegans is highly dependent on chemical structure. Bioorg Med Chem. 2013;21(18):5754-5769. [Content Brief]
[2]. Zhao M, et al. Major ascaroside pheromone component asc-C5 influences reproductive plasticity among isolates of the invasive species pinewood nematode. Integr Zool. 2021;16(6):893-907. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ascr#12 Related Classifications
HY-171720 Related Classifications
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