6 Results for "

pre-fusion F protein

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "pre-fusion F protein" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99804
CAS No.: 2429913-18-6
Synonyms: MK1654

Target:  

RSV

Research Areas:  

Infection

Clesrovimab (MK1654) is a humanized IgG1 monoclonal antibody targeting the respiratory syncytial virus (RSV) protein F. Clesrovimab binds to pre-fusion and post-fusion forms of RSV-A fusion protein with high affinity, with corresponding KD values of 71 pM and 480 pM, respectively. Clesrovimab is applicable for the research of RSV infection .
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Cat. No.: HY-P99647
CAS No.: 1257358-38-5
Synonyms: ALX-0171; VR-465

Target:  

RSV

Research Areas:  

Infection

Gontivimab (ALX-0171; VR-465) is a poent anti-RSV prefusion F protein nanobody with a KD value of 0.113 nM. Gontivimab shows antiviral activity. Gontivimab reduces the RSV load in the nose and lung .
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Cat. No.: HY-189244
CAS No.: 3103996-88-6
Target:  

RSV

Research Areas:  

Infection

RSV-IN-14 is an orally active pre-fusion F protein inhibitor of respiratory syncytial virus (RSV), with a Kd of 5.0 μM, and exhibits lung-targeted distribution properties. RSV-IN-14 binds to the central cavity of the trimeric pre-fusion F protein, locks it in the pre-fusion state, and inhibits the conformational changes required for membrane fusion to block viral entry. RSV-IN-14 suppresses respiratory syncytial virus-induced syncytium formation. RSV-IN-14 can be used in studies on respiratory syncytial virus infection .
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Cat. No.: HY-182030
Target:  

RSV

Research Areas:  

Infection

RSV fusion protein IN-1 is an orally active RSV pre-fusion F protein inhibitor with an IC50 of 0.10 nM against RSV. RSV fusion protein IN-1 forms stable hydrogen bonds and π-π stacking interactions with pre-fusion F protein to block viral fusion and entry. RSV fusion protein IN-1 suppresses RSV F protein expression in epithelial cells. RSV fusion protein IN-1 reduces viral burden in the lungs of RSV-infected murine models.RSV fusion protein IN-1 can be used for the research of respiratory syncytial virus (RSV) infection .
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Cat. No.: HY-P706196
Purity:  ≥ 90%, as determined by reducing SDS-PAGE; ≥ 90% as determined by SEC-MALS.
Synonyms: fusion glycoprotein F0; F; protein F; fusion protein
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P705638
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Human respiratory syncytial virus (RSV) (A2) prefusion glycoprotein F/ RSV-preF protein
Species:  
Virus
Source:  
CHO
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