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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
pylorus-ligated rats
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "pylorus-ligated rats" in MCE Product Catalog:
Cat. No.: HY-182643
CAS No.: 105150-87-6
Target:
Research Areas:
NO-794 is a histamine H2 receptor antagonist. NO-794 inhibits gastric acid secretion in pylorus-ligated rats. NO-794 can be used for the research of peptic ulcers .
Cat. No.: HY-W142456
CAS No.: 7535-59-3
Synonyms: N-Benzyl-L-pyroglutamic acid
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Research Areas:
(S)-1-Benzyl-5-carboxy-2-pyrrolidinone (N-Benzyl-L-pyroglutamic acid) is an orally active H +/K +-ATPase inhibitor. (S)-1-Benzyl-5-carboxy-2-pyrrolidinone reduces free acidity and total acidity in gastric juice. (S)-1-Benzyl-5-carboxy-2-pyrrolidinone decreases ulcer formation in pylorus-ligated rats. (S)-1-Benzyl-5-carboxy-2-pyrrolidinone can be used for the research of peptic ulcers .
Cat. No.: HY-182393
CAS No.: 126869-04-3
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IGN-2098 is an orally active, competitive histamine H2 receptor antagonist with a pA2 value of 7.32. IGN-2098 inhibits basal and stimulated gastric acid secretion. IGN-2098 accelerates ulcer healing, suppresses ulcer edge elevation, and protects gastric and duodenal mucosa from damage. IGN-2098 can be used in research related to gastric ulcers .
Cat. No.: HY-19153A
CAS No.: 157564-11-9
Synonyms: rel-TY-11345
Target:
Research Areas:
Nepaprazole sodium (rel-TY-11345) is a proton pump H+/K+-ATPase inhibitor. Nepaprazole sodium inhibits H+/K+-ATPase activity in rabbit gastric mucosal microsomes, with IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively, and its inhibitory activity is enhanced under weakly acidic conditions. Nepaprazole sodium inhibits basal and Tetragastrin (HY-125556)-stimulated gastric acid secretion. Nepaprazole sodium can be used in studies on gastric proton pump function, gastric acid secretion, and mechanisms related to peptic ulcers .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
