4 Results for "

pyruvate kinase M2 isoform

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "pyruvate kinase M2 isoform" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-126585
CAS No.: 3031-95-6
Purity:  99.57%
SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions .
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Cat. No.: HY-112253
CAS No.: 15978-08-2
D-Fructose 1-phosphate is a key intermediate metabolite in the fructose metabolic pathway. As a key signaling molecule linking fructose metabolism and glucose metabolic regulation, D-Fructose 1-phosphate acts as an allosteric modulator to counteract the inhibitory effect of the glucokinase-regulatory protein complex, thereby finely regulating the direction of hepatic glucose metabolism at the substrate level .
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Cat. No.: HY-111936
CAS No.: 562867-96-3
Synonyms: BML283
Target:  

Pyruvate Kinase

Research Areas:  

Cancer

ML083 is a member of a series of highly specific allosteric activators for the tumor-specific isoform of human pyruvate kinase (M2 isoform). ML083 affects the cooperativity of phosphoenolpyruvate (PEP) binding. ML083 can be used in the research of tumors .
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Cat. No.: HY-126585S
SAICAR-d3 is the deuterium labeled SAICAR. SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions .
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