7 Results for "

rat thoracic aorta

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "rat thoracic aorta" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-N6771
CAS No.: 18172-33-3
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC50 value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B [1][4][5].
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Cat. No.: HY-122215
CAS No.: 62774-96-3
Synonyms: N-696
Target:  

Adrenergic Receptor

Research Areas:  

Endocrinology

Tilisolol hydrochloride (N-696) is a non-selective β-adrenergic antagonist with vasodilatory and hypotensive activities. Tilisolol hydrochloride exerts its effects in canine coronary arteries by opening ATP-sensitive K+ channels. Tilisolol hydrochloride exhibits concentration-dependent relaxation in KCl-precontracted rat thoracic aorta. Tilisolol hydrochloride reduces diastolic blood pressure in a dose-dependent manner and slightly increases heart rate in spinal cord stimulated rats .
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Cat. No.: HY-108055
CAS No.: 669089-53-6
Urantide is a selective and competitive urotensin-II (UT) receptor antagonist peptide (pKB=8.3) that blocks human urotensin-II (hU-II)-induced contractions in rat thoracic aorta ex vivo. Urantide can be used to study the (patho)physiological role of hU-II in the mammalian cardiovascular system .
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Cat. No.: HY-N11925
CAS No.: 112923-64-5
(+)-Osbeckic acid is a vasorelaxatant that can be isolated from Tartary Buckwheat. (+)-Osbeckic acid has a potent vasorelaxant effect in Sprague-Dawley rat thoracic aorta rings with an EC50 of 887 μM .
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Cat. No.: HY-N6771S
CAS No.: 2815925-39-2
Cyclopiazonic acid- 13C20 is the 13C-labeled Cyclopiazonic acid (HY-N6771). Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC50 value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B .
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Cat. No.: HY-N20728
CAS No.: 2221029-53-2
25-Methoxyalisol F is a regulator of NOX4 and phosphorylated Nrf2 with anti-pulmonary fibrosis activity. 25-Methoxyalisol F modulates the NOX4-Nrf2 signaling pathway, regulates the expression of NOX4 and p-Nrf2, and ameliorates TGF-β1-induced cellular damage. 25-Methoxyalisol F can be used in studies related to pulmonary fibrosis .
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Cat. No.: HY-182701
CAS No.: 149685-89-2
5-HT3 antagonist-7 (Compound 7e) is a competitive and selective 5-HT3 receptor antagonist. 5-HT3 antagonist-7 inhibits 5-HT-induced contractions in guinea pig ileum and guinea pig thoracic aorta. 5-HT3 antagonist-7 prevents 2-methyl-5-HT-induced vomiting episodes in ferrets .
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