62774-96-3
Chemical Structure
Tilisolol hydrochloride
Synonym(s): N-696
- No. CAS: 62774-96-3
- Formula:C17H25ClN2O3
- Molecular Weight:340.85
IUPAC Name: 4-(3-(tert-butylamino)-2-hydroxypropoxy)-2-methylisoquinolin-1(2H)-one hydrochloride
InChIKey: SGPGESCZOCHFCL-UHFFFAOYSA-N
SMILES: O=C1C2=C(C(OCC(CNC(C)(C)C)O)=CN1C)C=CC=C2.Cl
Biological Activity: Tilisolol hydrochloride (N-696) is a non-selective β-adrenergic antagonist with vasodilatory and hypotensive activities. Tilisolol hydrochloride exerts its effects in canine coronary arteries by opening ATP-sensitive K+ channels. Tilisolol hydrochloride exhibits concentration-dependent relaxation in KCl-precontracted rat thoracic aorta. Tilisolol hydrochloride reduces diastolic blood pressure in a dose-dependent manner and slightly increases heart rate in spinal cord stimulated rats[1].
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Tilisolol hydrochloride | 99.71% | Tilisolol hydrochloride (N-696) is a non-selective β-adrenergic antagonist with vasodilatory and hypotensive activities. Tilisolol hydrochloride exerts its effects in canine coronary arteries by opening ATP-sensitive K+ channels. Tilisolol hydrochloride exhibits concentration-dependent relaxation in KCl-precontracted rat thoracic aorta. Tilisolol hydrochloride reduces diastolic blood pressure in a dose-dependent manner and slightly increases heart rate in spinal cord stimulated rats. | ||||||||||||||||||||
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