125 Results for "

sphingolipid

" in MedChemExpress (MCE) Product Catalog:
Products (125)

125 Results for "sphingolipid" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-N6798
CAS No.: 35891-70-4
Synonyms: Thermozymocidin; ISP-I
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection .
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9
9 Cited Publications
Cat. No.: HY-N6719
CAS No.: 116355-83-0
Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin .
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2
2 Cited Publications
Cat. No.: HY-B1513
CAS No.: 10016-20-3
α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids .
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1
1 Cited Publications
Cat. No.: HY-113498
CAS No.: 85187-10-6
Purity:  ≥98.0%
Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease .
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1
1 Cited Publications
Cat. No.: HY-113116
CAS No.: 19794-97-9
Purity:  ≥99.0%
Synonyms: D-erythro-Dihydrosphingosine 1-phosphate
Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes .
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1
1 Cited Publications
Cat. No.: HY-N7814
CAS No.: 764-67-0
2-Hydroxypalmitic acid is an intermediate in the phytosphingosine metabolic pathway. 2-Hydroxypalmitic acid is exclusively incorporated into sphingolipids and not used for other lipids. 2-Hydroxypalmitic acid promotes the production of odd-carbon phosphatidylcholine species. 2-Hydroxypalmitic acid is applicable to studies of Saccharomyces cerevisiae infection .
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1
1 Cited Publications
Cat. No.: HY-P76553
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PSAP; Saposin-A; Prev. GLBA; Saposin-C; Prev. SAP1; Saposin-D; Prev. SAP2; Variant Gaucher Disease And Variant Metachromatic Leukodystrophy; sphingolipid Activator Protein-1; Alternative Protein PSAP; sphingolipid Activator Protein-2; PARK24; Proactivator
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P77159
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PSAP; Saposin-A; Prev. GLBA; Saposin-C; Prev. SAP1; Saposin-D; Prev. SAP2; Variant Gaucher Disease And Variant Metachromatic Leukodystrophy; sphingolipid Activator Protein-1; Alternative Protein PSAP; sphingolipid Activator Protein-2; PARK24; Proactivator
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-124758
CAS No.: 1841409-92-4
Purity:  99.34%
Research Areas:  

Metabolic Disease Cancer

SH-BC-893 is an orally active anti-neoplastic sphingolipid analog. SH-BC-893 also protects from ceramide-induced mitochondrial dysfunction and corrects diet-induced obesity. SH-BC-893 can be used for the research of cancer and obesity .
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Cat. No.: HY-134508A
CAS No.: 102917-80-6
Purity:  99%
Research Areas:  

Others

C24-Ceramide (d18:1/24:0) is a sphingolipid that can be used for the lipid membranes composed. C24-Ceramide (d18:1/24:0) induces time-dependent changes in membrane properties. C24-Ceramide (d18:1/24:0) induces membrane reorganization .
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Cat. No.: HY-153830
CAS No.: 4201-62-1
Synonyms: C16 Lactosylceramide (d18:1/16:0)
LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0)) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases .
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Cat. No.: HY-W012017
CAS No.: 2507-55-3
Target:  

Enterovirus

Research Areas:  

Infection

2-Hydroxytetradecanoic acid is a 2-hydroxy long-chain fatty acid and a sphingolipid component. 2-Hydroxytetradecanoic acid inhibits cleavage between the enterovirus capsid proteins VP4 and VP2. 2-Hydroxytetradecanoic acid exhibits antiviral activity .
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Cat. No.: HY-141632
CAS No.: 32164-02-6
Synonyms: Heptadecasphinganine
Target:  

Bacterial

Research Areas:  

Infection Neurological Disease

Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine. Sphinganine-C17 inhibits the growth of Candida glabrata and Candida albicans with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both. Sphinganine-C17 can be used as an internal standard for the chromatographic analysis of sphingosine compounds .
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Cat. No.: HY-168763
CAS No.: 844866-89-3
Target:  

Liposome

Research Areas:  

Metabolic Disease

C23 Phytoceramide is a long-chain sphingolipid, which is found in C. sinensis .
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Cat. No.: HY-165136
CAS No.: 475662-40-9
Synonyms: SMs (buttermilk)
Target:  

Endogenous Metabolite

Research Areas:  

Others

Sphingomyelins, milk (SMs (buttermilk)) are compounds studied in sphingolipids, which play important roles in various biological processes.
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Cat. No.: HY-P2982
CAS No.: 128543-23-7
Target:  

Liposome

Research Areas:  

Metabolic Disease

Ceramide 1-phosphate is a bioactive lipid and one of the key components of sphingolipids. Ceramide 1-phosphate playing diverse roles in cellular behaviors such as cell differentiation, migration, proliferation and death .
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Cat. No.: HY-138875
CAS No.: 13018-48-9
Purity:  99.90%
Tetraacetylphytosphingosine is a sphingolipid metabolite produced by phytosphingosine acetylation. Tetraacetylphytosphingosine exerts its inhibitory action on angiogenesis through the inhibition of MAPK activation and intracellular calcium increase . Tetraacetylphytosphingosine induces apoptosis in HaCaT cells .
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Cat. No.: HY-N10706A
CAS No.: 35299-94-6
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

3-Keto sphinganine (d18:0) hydrochloride serves as the substrate for 3-keto-dihydrosphingosine reductase in the de novo sphingolipid synthesis pathway, and is a key intermediate in the de novo synthesis of sphingoid long-chain bases. 3-Keto sphinganine (d18:0) hydrochloride can be used in studies related to thrombocytopenia, anemia .
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Cat. No.: HY-165677
CAS No.: 74645-25-3
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

C22 Galactosylceramide is a sphingolipid present in the central nervous system, exhibiting elevated levels in the spinal cord of mice on a methionine-restricted diet, while not affecting the brain or liver; furthermore, it has been identified in the postmortem hippocampus of Alzheimer's disease patients.
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Cat. No.: HY-116017
CAS No.: 111122-57-7
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

C10 ceramide is an endogenous, bioactive sphingolipid,
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