1841409-92-4
1841409-92-4
Chemical Structure
SH-BC-893
- CAS 番号: 1841409-92-4
- Formula:C19H32ClNO
- Molecular Weight:325.92
IUPAC Name: ((2S,3R)-3-(4-octylphenyl)pyrrolidin-2-yl)methanol hydrochloride
InChIKey: QJRPLIVTEDTSKX-STYNFMPRSA-N
SMILES: OC[C@H]1NCC[C@@H]1C2=CC=C(CCCCCCCC)C=C2.Cl
Biological Activity: SH-BC-893 is an orally active anti-neoplastic sphingolipid analog. SH-BC-893 also protects from ceramide-induced mitochondrial dysfunction and corrects diet-induced obesity. SH-BC-893 can be used for the research of cancer and obesity[1][2].
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SH-BC-893 | 97.31% | SH-BC-893 is an orally active anti-neoplastic sphingolipid analog. SH-BC-893 also protects from ceramide-induced mitochondrial dysfunction and corrects diet-induced obesity. SH-BC-893 can be used for the research of cancer and obesity. | ||||||||||||||||||||
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References
- [1]. Kubiniok, Peter et al. Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs. Molecular & cellular proteomics : MCP vol. 18,3 (2019): 408-422. [Content Brief]
- [2]. Jayashankar, Vaishali et al. Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity. EMBO molecular medicine vol. 13,8 (2021): e13086. [Content Brief]
