10016-20-3
Chemical Structure
α-Cyclodextrin
- CAS No.: 10016-20-3
- Formula:C36H60O30
- Molecular Weight:972.84
InChIKey: HFHDHCJBZVLPGP-RWMJIURBSA-N
SMILES: OC[C@@H](O[C@@](O[C@]([C@@H]1O)([H])[C@H](O[C@@](O[C@]([C@@H]2O)([H])[C@H](O[C@@](O[C@@]3([H])[C@@H]4O)([H])[C@@H]2O)CO)([H])[C@@H]1O)CO)([H])[C@@H]5O)[C@](O[C@](O[C@H](CO)[C@](O[C@](O[C@H](CO)[C@](O[C@](O[C@@H]3CO)([H])[C@@H]4O)([H])[C@@H]6O)([H])[C@@H]6O)([H])[C@@H]7O)([H])[C@@H]7O)([H])[C@@H]5O
Biological Activity: α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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α-Cyclodextrin | 99.96% | α-Cyclodextrin (α-CD) is a soluble fiber derived from corn. α-Cyclodextrin can deplete sphingolipids and phospholipids from cell membranes. α-Cyclodextrin interacts with tubulin. α-Cyclodextrin improves defenses against SARS-CoV-2 infection. α-Cyclodextrin enhances the anticancer efficacy of Crcumin (HY-N0005) against breast, lung and cervical cancer. α-Cyclodextrin has beneficial effects on body weight and blood lipids. | ||||||||||||||||||||
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References
- [1]. Comerford KB, et al. The beneficial effects of α-cyclodextrin on blood lipids and weight loss in healthy humans. Obesity (Silver Spring). 2011 Jun;19(6):1200-4. [Content Brief]
- [2]. Paolacci S, et al. In vitro and clinical studies on the efficacy of α-cyclodextrin and hydroxytyrosol against SARS-CoV-2 infection. Eur Rev Med Pharmacol Sci. 2021 Dec;25(1 Suppl):81-89. [Content Brief]
- [3]. Jana B, et al. α-Cyclodextrin Interacts Close to Vinblastine Site of Tubulin and Delivers Curcumin Preferentially to the Tubulin Surface of Cancer Cell. ACS Appl Mater Interfaces. 2016 Jun 8;8(22):13793-803. [Content Brief]
- [4]. Lina BA, et al. Subchronic oral toxicity studies with alpha-cyclodextrin in rats. Regul Toxicol Pharmacol. 2004 Jun;39 Suppl 1:S14-26. [Content Brief]
- [5]. Lina BA, et al. Subchronic (13-week) oral toxicity study of alpha-cyclodextrin in dogs. Regul Toxicol Pharmacol. 2004 Jun;39 Suppl 1:S27-33. [Content Brief]
