Mal-β-CD
Based on 2 publication(s) in Google Scholar
Mal-β-CD is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 104723-60-6
- Formula: C54H90O45
- Molecular Weight:1459.27
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Storage:Powder -20°C, 3 years , 4°C, 2 years
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Mal-β-CD
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Biological Activity
Mal-β-CD removes cellular cholesterol forming inclusion complexes, while Mal-β-CD-induced lack of cellular cholesterol is replenished by the addition of cholesterol/Mal-β-CD inclusion complex (CLM) without cytotoxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 104723-60-6
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Appearance Solid
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Molecular Weight 1459.27
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Formula C54H90O45
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Color White to off-white
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SMILES
O[C@@H]1[C@@H](CO)O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](OC[C@H]3O[C@H](O[C@@H]4[C@@H](CO)O[C@H](O[C@@H]5[C@@H](CO)O[C@H](O6)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@@H]3O[C@H]7O[C@H](CO)[C@@H](O[C@@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]9[C@H](O)[C@@H](O)[C@H](OC%10[C@H](O)[C@@H](O)[C@H]6[C@@H](CO)O%10)[C@@H](CO)O9)[C@@H](CO)O8)[C@H](O)[C@H]7O)O[C@@H]2CO)[C@H](O)[C@H]1O
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Synonyms
6-O-alpha-D-Maltosyl-beta-cyclodextrin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years
Publications (2)
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Journal Impact Factor
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Most Recent
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Biochem Biophys Res Commun
Avapritinib efficacy in primary hepatic neuroendocrine carcinoma with elevated PDGFRA expression: Insights from a PDX model study. [Abstract]2024 Aug 6:736:150504. PMID: 39121673 -
Biosci Biotechnol Biochem
Solubilization and stabilization of lipoic acid trisulfide by creation of various β-cyclodextrin clathrates. [Abstract]2024 May 22;88(6):601-607. PMID: 38569654
Solvent & Solubility
DMSO : ≥ 100 mg/mL (68.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 60.5 mg/mL (41.46 mM)
* "≥" means soluble, but saturation unknown.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (286 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 0.6853 mL | 3.4264 mL | 6.8527 mL | 17.1319 mL |
| 5 mM | 0.1371 mL | 0.6853 mL | 1.3705 mL | 3.4264 mL | |
| 10 mM | 0.0685 mL | 0.3426 mL | 0.6853 mL | 1.7132 mL | |
| 15 mM | 0.0457 mL | 0.2284 mL | 0.4568 mL | 1.1421 mL | |
| 20 mM | 0.0343 mL | 0.1713 mL | 0.3426 mL | 0.8566 mL | |
| 25 mM | 0.0274 mL | 0.1371 mL | 0.2741 mL | 0.6853 mL | |
| 30 mM | 0.0228 mL | 0.1142 mL | 0.2284 mL | 0.5711 mL | |
| 40 mM | 0.0171 mL | 0.0857 mL | 0.1713 mL | 0.4283 mL | |
| DMSO | 50 mM | 0.0137 mL | 0.0685 mL | 0.1371 mL | 0.3426 mL |
| 60 mM | 0.0114 mL | 0.0571 mL | 0.1142 mL | 0.2855 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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