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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10073 Results for "
synthesis,
" in MedChemExpress (MCE) Product Catalog:
Products (10073)
10073 Results for "synthesis," in MCE Product Catalog:
436
Target:
436
436 Publications Verification
Synonyms: CL13900 dihydrochloride
Category:
Infection Microorganisms Antibiotics Resistance Selection Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
344
290
Research Areas:
Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .
232
232 Cited Publications
Cat. No.: HY-17371
CAS No.: 61825-94-3
Target:
Research Areas:
Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research .
226
Target:
Research Areas:
Remdesivir (GS-5734) is a nucleoside analogue with effective antiviral activity. Remdesivir can inhibit the synthesis of viral DNA or RNA. Remdesivir can be used for the research of infection, such as SARS-CoV and MHV infection .
226
226 Cited Publications
Synonyms: MLN4924 hydrochloride
Target:
Research Areas:
Pevonedistat (MLN4924) hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM. Pevonedistat hydrochloride induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat hydrochloride suppresses the growth of human tumour xenografts in mice .
212
212 Cited Publications
Cat. No.: HY-17565A
CAS No.: 67763-87-5
Target:
Research Areas:
Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic .
212
Category:
Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Anticancer Disease Research Fields Other Antibiotics Cancer
Target:
164
164 Cited Publications
Synonyms: Adenosine 5'-triphosphate disodium salt, 100 mM Solution, PCR Grade
155
111
Research Areas:
Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
105
105 Cited Publications
Synonyms: Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride
Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.
105
105 Cited Publications
Synonyms: Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C
100
Category:
Disease Research Antibacterial Other Antibiotics Microorganisms Plant Cell Culture Antibiotics Phenols Polyphenols Disease Research Fields Cancer
Target:
95
Research Areas:
Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.
79
79 Cited Publications
Synonyms: 7-Ethyl-10-hydroxycamptothecin
73
73 Cited Publications
Cat. No.: HY-K1057
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.
71
71 Cited Publications
Target:
Research Areas:
CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively .
71
71 Cited Publications
Cat. No.: HY-13323A
Purity: 99.41%
Target:
Research Areas:
CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
