4 Results for "

systemic amyloidosis

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "systemic amyloidosis" in MCE Product Catalog:

Cat. No.: HY-P99358
CAS No.: 1662664-56-3
Synonyms: GSK 2398852; Anti-Serum Amyloid P/SAP Reference Antibody (dezamizumab)

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Dezamizumab (GSK 2398852) is a fully humanized clonal IgG1 antibody against serum amyloid P component (SAP) with complement activation and amyloid clearance-inducing activities. Dezamizumab binds to SAP associated with amyloid deposits to form complexes that activate complement and mediate phagocytic clearance, triggering activation of the classical complement pathway. Dezamizumab can be used for the research of systemic amyloidosis .
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Cat. No.: HY-P99105
CAS No.: 2414866-63-8
Synonyms: CAEL-101

Research Areas:  

Neurological Disease

Anselamimab (CAEL-101) is a chimeric monoclonal antibody for systemic light chain (AL) amyloidosis. Anselamimab can promote phagocytic destruction and subsequent clearance of amyloid deposits. Anselamimab can be used in the research of amyloidosis .
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Cat. No.: HY-19771
CAS No.: 1819986-22-5
Synonyms: GSK294; amyloid P-IN-1
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

GSK3039294 is an orally active pro-drug of Miridesap (HY-101861), a circulating serum amyloid P component depleter. GSK3039294 undergoes hydrolysis to form miridesap via a monoester intermediate. GSK3039294 can be used for the research of systemic amyloidosis .
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Cat. No.: HY-P991039
CAS No.: 2937458-25-6
Synonyms: AT-02

Target:  

Amyloid-β

Research Areas:  

Inflammation/Immunology

Zamubafusp alfa (AT-02) is an immunoglobulin-peptide fusion protein consisting of a humanized IgG1 and the pan-amyloid reactive peptide p5R. Zamubafusp alfa binds to two ubiquitous components of all amyloids, namely amyloid fibrils and highly sulfated heparan sulfate glycans. Zamubafusp alfa enhances macrophage phagocytosis for amyloid clearance and can be used in research related to systemic amyloidosis .
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