2414866-63-8
Chemical Structure
Anselamimab
Synonym(s): CAEL-101
- CAS No.: 2414866-63-8
- Formula:N/A
- Molecular Weight:(144.42 kDa)
SMILES: [Anselamimab]
Biological Activity: Anselamimab (CAEL-101) is a chimeric monoclonal antibody for systemic light chain (AL) amyloidosis. Anselamimab can promote phagocytic destruction and subsequent clearance of amyloid deposits. Anselamimab can be used in the research of amyloidosis[1][2].
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Anselamimab | 98.96% | Anselamimab (CAEL-101) is a chimeric monoclonal antibody for systemic light chain (AL) amyloidosis. Anselamimab can promote phagocytic destruction and subsequent clearance of amyloid deposits. Anselamimab can be used in the research of amyloidosis. | ||||||||||||||||||||
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- [1]. Fu J, et al. Personalizing amyloidosis therapy with real time PET imaging of fibril-reactive monoclonal antibody cael-101. Blood, 2018, 132: 1003.
- [2]. Edwards CV, et al. Phase 1a/b study of monoclonal antibody CAEL-101 (11-1F4) in patients with AL amyloidosis. Blood. 2021 Dec 23;138(25):2632-2641. [Content Brief]
Keywords