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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
110 Results for "
therapeutic agents
" in MedChemExpress (MCE) Product Catalog:
Products (110)
110 Results for "therapeutic agents" in MCE Product Catalog:
379
379 Publications Verification
Synonyms: DMSO, meets analytical specification of Ch.P.
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.
53
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.
50
50 Cited Publications
Synonyms: MK-933; CD-5024; K-237
4
4 Cited Publications
Target:
Research Areas:
PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA .
4
4 Cited Publications
Synonyms: EMA401; PD-126055; (S)-EMA400
Target:
Research Areas:
Olodanrigan (EMA401) is a highly selective, orally active, peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist. It is under development as a neuropathic pain therapeutic agent. Olodanrigan (EMA401) analgesic action appears to involve inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons .
4
4 Cited Publications
Cat. No.: HY-N0211
CAS No.: 17086-76-9
1
1 Cited Publications
Synonyms: O-Methylhydroxylamine hydrochloride
Target:
Research Areas:
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .
1
1 Cited Publications
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) . Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
1
1 Cited Publications
Research Areas:
Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
1
Target:
1
1 Cited Publications
Cat. No.: HY-N0074
CAS No.: 26091-79-2
Category:
Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
SRI 37892 is a small molecule compound inhibitor of Frizzled protein 7 (Fzd7) with inhibitory activity against cancer cell proliferation (IC50=2μM). SRI 37892 significantly blocks Wnt/Fzd7 signaling. SRI 3789 can be used in the research of developing cancer therapeutic agents .
Synonyms: BSH
Target:
Research Areas:
Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity .
Cat. No.: HY-B0758
CAS No.: 30751-05-4
Target:
Research Areas:
Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties .
Target:
Research Areas:
PF-5006739 is a potent and selective inhibitor of CK1δ/ε with IC50s of 3.9 nM and 17.0 nM, respectively. PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1δ/ε and high kinome selectivity. PF-5006739 attenuats opioid agent-seeking behavior in a rodent operant reinstatement model in animals in a dose-dependent manner . PF-5006739 improves glucose tolerance in both diet-induced obesity (DIO) and genetic (ob/ob) mice models of obesity .
Cat. No.: HY-Y0320GL
CAS No.: 67-68-5
Synonyms: DMSO (GMP Like)
Synonyms: RGH-896
Target:
Research Areas:
Radiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions .
Cat. No.: HY-P4116
CAS No.: 2293160-09-3
Synonyms: pHLIP
Target:
Research Areas:
Category:
Metabolic Disease Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields
Target:
Cat. No.: HY-114376
CAS No.: 12448-24-7
Synonyms: BSH-10B12
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
