3 Results for "

tropical marine sponge

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "tropical marine sponge" in MCE Product Catalog:

Cat. No.: HY-N15748
CAS No.: 287974-44-1
Synonyms: (-)-Pelorol
Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC50 of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC50 values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria .
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Cat. No.: HY-N1662
CAS No.: 203524-64-5
2,4,6,6-Tetramethyl-3(6H)-pyridinone is a natural product that can be isolated from the tropical marine sponge Agelas oroides .
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Cat. No.: HY-L143
60 compounds

Oceans cover more than 70% of the Earth’s surface and host a huge species diversity. Marine organisms are considered the most recent source of bioactive natural products after terrestrial plants and nonmarine microorganisms. Marine biological sources are taxonomically diverse and include sponges, tunicates, corals, mollusks, fungi, and sediment-derived bacteria.

Marine organisms can produce a plethora of small molecules with novel chemical structures and potent biological properties, being a rich source for the discovery of pharmacologically active compounds, already with several marine-derived agents approved as drugs. Ziconotide, a peptide originally discovered in a tropical cone snail, was the first marine-derived compound to be approved in the United States in December 2004 for the treatment of pain. Then, in October 2007, Trabectedin became the first marine anticancer drug to be approved in the European Union.

MCE offers a unique collection of 60 marine-sourced natural products which can be used for drug discovery for high throughput screening (HTS) and high content screening (HCS). MCE marine-sourced natural product library is an important source for drug discovery and development.