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Results for "

vascular grafts

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Biochemical Assay Reagents

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125864
    Fibrinogen (Bovine)
    2 Publications Verification

    		 Interleukin Related NF-κB Inflammation/Immunology
    Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .
    Fibrinogen (Bovine)
  • HY-Y0850U8
    PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)

    Polyvinyl alcohol (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization); Poly(Ethenol) (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)

    		 Biochemical Assay Reagents Others
    PVA (Polyvinyl alcohol; Poly(Ethenol)) (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) is a semicrystalline synthetic polymer with excellent biocompatibility and biodegradability, which is non-toxic and non-mutagenic upon oral administration in the human body. PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) can serve as an excipient, inhibitor or coating agent to prepare solid dispersions by absorbing water and inhibiting drug crystal nucleation and growth, and can encapsulate insulin-like growth factor-1. PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) can form physically crosslinked cryogels and degradable films, and is widely used in the construction of vascular grafts, the synthesis of articular cartilage, and studies on dry or minimally invasive ex vivo wounds. PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization) also promotes hydrogen peroxide generation and enhances the redox cycle of iron species, thus acting as a sacrificial agent to effectively degrade pollutants .
    PVA (Mw 47000, 98-99% hydrolyzed, ~1000 polymerization)
  • HY-Y0850U2
    PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)

    Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)

    		 Biochemical Assay Reagents Others
    PVA (Polyvinyl alcohol; Poly(Ethenol)) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) is a non-toxic, biodegradable, and highly biocompatible semicrystalline synthetic polymer. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) acts as a coating agent to improve tableting performance, and can be cross-linked with sodium trimetaphosphate to prepare tubular vascular grafts or form hydrogels for use as artificial articular cartilage and sustained-release matrices for growth factors. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) enhances the redox cycle of iron species in photo-assisted Fenton reactions to simultaneously generate hydrogen peroxide and degrade pollutants, enabling integrated sustainable waste management and water treatment. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) is used in the manufacture of biodegradable films and in studies of dry or minimally invasive ex vivo wounds, but cannot form freeze-thaw cross-linked solid sheets for wound dressings .
    PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)
  • HY-29347
    Ocrylate

    		Biochemical Assay Reagents Cardiovascular Disease
    Ocrylate is a tissue adhesive that contains an 8-carbon alkyl cyanoacrylate in its structure. Ocrylate can be used in research on gastric fundal varices, bone and cartilage grafting, cerebrospinal fluid leakage repair, and skin closure. Additionally, the rapid polymerization property of Ocrylate makes it suitable for inhibiting vascular embolization .
    Ocrylate
  • HY-125864D
    Rabbit Fibrinogen

    		Interleukin Related NF-κB Cardiovascular Disease
    Rabbit Fibrinogen is a native fibrinogen from rabbit plasma. Fibrinogen is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .
    Rabbit Fibrinogen
  • HY-12514
    NK3201

    		Ser/Thr Protease
    NK3201 is an orally active chymase inhibitor (IC50: 2.5, 1.2, and 28 nM for human, dog and hamster chymase). NK3201 inhibits Bleomycin (HY-17565)-induced pulmonary fibrosis. NK3201 inhibits vascular proliferation in grafted vein .
    NK3201

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