(E)-MDL72274 hydrochloride
(E)-MDL72274 hydrochloride is a semicarbazide-sensitive amine oxidase (SSAO) inhibitor with an IC50 value of 0.74-1.42 μM. (E)-MDL72274 hydrochloride inhibits allylamine-induced excessive contraction of isolated coronary artery bypass graft vessels. (E)-MDL72274 hydrochloride can be used in studies related to vasospasm.
For research use only. We do not sell to patients.
- CAS No.: 85278-24-6
- Formula: C9H11Cl2N
- Molecular Weight:204.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
(E)-MDL72274 (1 nM-0.1 mM; 30 min) hydrochloride potently inhibits SSAO activity in homogenized human internal mammary artery, radial artery, and saphenous vein with IC50 values ranging from 0.74-1.42 μM, and completely blocks SSAO activity at 0.1 mM[1].
(E)-MDL72274 (0.1 mM; 20 min) hydrochloride completely blocks Allylamine-induced hypercontraction and associated vascular dysfunction in isolated human internal mammary artery rings by inhibiting SSAO activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 85278-24-6
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Molecular Weight 204.10
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Formula C9H11Cl2N
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SMILES
Cl/C=C(C1=CC=CC=C1)/CN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(E)-MDL72274 hydrochloride Related Classifications
HY-111290 Related Classifications
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