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Cat. No.: HY-101436AR

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Sematilide hydrochloride (Standard)

(Synonyms: CK-1752 hydrochloride (Standard))

Sematilide (hydrochloride) (Standard) is the analytical standard of Sematilide (hydrochloride). This product is intended for research and analytical applications. Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 101526-62-9
Formula: C₁₄H₂₄ClN₃O₃S
Molecular Weight:349.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Sematilide hydrochloride (Standard) Chemical Structure

CAS No.: 101526-62-9

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 101526-62-9
Molecular Weight 349.88
Formula C₁₄H₂₄ClN₃O₃S
SMILES

O=C(NCCN(CC)CC)C1=CC=C(NS(=O)(C)=O)C=C1.Cl
Synonyms

CK-1752 hydrochloride (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Ishii Y, et al. Effects of Sematilide, a novel class III antiarrhythmic agent, on membrane currents in rabbit atrial myocytes. Eur J Pharmacol. 1997 Jul 23;331(2-3):295-302. [Content Brief]

[2]. Stanley S. Greenberg, et al. Pharmacology of Sematilide, a non-quaternary class III antiarrhythmic agent.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Sematilide hydrochloride (Standard)

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Sematilide hydrochloride (Standard)

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Sematilide hydrochloride (Standard) Related Classifications

HY-101436AR Related Classifications