101526-62-9
101526-62-9
Chemical Structure
Sematilide hydrochloride
Synonym(s): CK-1752 hydrochloride
- CAS No.: 101526-62-9
- Formula:C14H24ClN3O3S
- Molecular Weight:349.88
IUPAC Name: N-(2-(diethylamino)ethyl)-4-(methylsulfonamido)benzamide hydrochloride
InChIKey: OKXAJGDKHKNFAX-UHFFFAOYSA-N
SMILES: O=C(NCCN(CC)CC)C1=CC=C(NS(=O)(C)=O)C=C1.Cl
Biological Activity: Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent[1].
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Sematilide hydrochloride | 99.85% | Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent. | ||||||||||||||||||||
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Sematilide hydrochloride (Standard) | ≥98% | Sematilide (hydrochloride) (Standard) is the analytical standard of Sematilide (hydrochloride). This product is intended for research and analytical applications. Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-101436Sematilide -
Similarity Score 0.82
HY-101433RN-Acetylprocainamide hydrochloride (Standard) -
Similarity Score 0.81
HY-B1109N-Acetylprocainamide -
Similarity Score 0.79
HY-A0084Procainamide hydrochloride -
Similarity Score 0.78
HY-A0084AProcainamide -
Similarity Score 0.72
HY-111193ADeclopramide hydrochloride -
Similarity Score 0.71
HY-111193Declopramide -
Similarity Score 0.68
HY-159738N-(2-(Diethylamino)ethyl)-2-iodobenzamide -
Similarity Score 0.68
HY-B1196Tiapride hydrochloride -
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