DCI-Br-3
DCI-Br-3 is a rapid, highly sensitive, and selective probe to monitor thiols in the epileptic brain. (λex=537 nm, λem=675 nm).DCI-Br-3 can effectively cross the blood-brain barrier (BBB).
For research use only. We do not sell to patients.
- Formula: C25H20BrN3O2
- Molecular Weight:474.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
DCI-Br-3 (0-20 μM; 30 min; SH-SY5Y cells) increases intracellular fluorescence in a concentration-dependent manner and has a good response to thiols in SH-SY5Y cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c mice (6 weeks of age)[1]
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Dosage:5 mg/kg
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Administration:intraperitoneal injection
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Result:Crossed the blood−brain barrier and had red fluorescence in BALB/c mice.
Emission (Em)
675
Excitation (Ex)
537
Chemical Information
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Molecular Weight 474.35
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Formula C25H20BrN3O2
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SMILES
N#C/C(C#N)=C1CC(C)(C)CC(/C=C/C2=CC=C(OC(C3=CC=NC=C3)=O)C(Br)=C2)=C\1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DCI-Br-3 Related Classifications
HY-151615 Related Classifications
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