2. PROTAC Protein Tyrosine Kinase/RTK
  3. SNIPERs Bcr-Abl
  4. SNIPER(ABL)-049

SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 100 μM.

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SNIPER(ABL)-049

SNIPER(ABL)-049 Chemische Struktur

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SNIPER(ABL)-049 Related Antibodies

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Beschreibung

SNIPER(ABL)-049, conjugating Imatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 100 μM[1].

Molekulargewicht

959.14

Formel

C52H66N10O8
SMILES

CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC4=CC=CC=C4)N)=O)=O)=O)CC3)C=C2)=O)C=C1NC5=NC=CC(C6=CC=CN=C6)=N5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

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SNIPER(ABL)-049 Related Classifications

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Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SNIPER(ABL)-049SNIPERsBcr-AblPROTACs, IAP-dependent Protein Eraser, Specific and Nongenetic inhibitor of apoptosis protein [IAP]-dependent Protein ErasersInhibitorinhibitorinhibit

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