1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. Strictosidinic acid

Strictosidinic acid 

Cat. No.: HY-N7514
Handling Instructions

Strictosidinic acid, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice.

For research use only. We do not sell to patients.

Strictosidinic acid Chemical Structure

Strictosidinic acid Chemical Structure

CAS No. : 150148-81-5

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Description

Strictosidinic acid, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice[1][2].

IC50 & Target[1]

5-HT Receptor

 

In Vivo

Strictosidinic acid (20 μg/μl; intra-hippocampal injection) causes a significance of 83.5% reduction in 5-HT levels. Strictosidinic acid (10 mg/kg; i.p.) causes a 63.4% reduction in 5-HT levels and a 67.4% reduction in DOPAC values in male Wistar rats, weighing 200-250 g[1].

Molecular Weight

516.54

Formula

C₂₆H₃₂N₂O₉

CAS No.

150148-81-5

SMILES
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Strictosidinic acid5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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