TopoII/tubulin-IN-1
TopoII/tubulin-IN-1 (Compound 1B8) is a TopoII/tubulin inhibitor. TopoII/tubulin-IN-1 can inhibit the proliferation and the level of ROS of tumor cells, induce apoptosis and cell cycle arrest of tumor cells, but has no significant cytotoxicity to normal cells. TopoII/tubulin-IN-1 has antitumor activity.
For research use only. We do not sell to patients.
- Formula: C21H18ClN5O3
- Molecular Weight:423.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Topoisomerase Isoforms
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Biological Activity
Description
Chemical Information
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Molecular Weight 423.85
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Formula C21H18ClN5O3
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SMILES
COC1=C(OC)C(OC)=CC(C2=CC(C3=CC=CC=C3Cl)=NC(N4C=NN=C4)=N2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)