2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Topoisomerase I/II inhibitor 7

Topoisomerase I/II inhibitor 7 (Compound 5h) is a Topoisomerase I/II inhibitor.

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Topoisomerase I/II inhibitor 7

Topoisomerase I/II inhibitor 7 Chemical Structure

CAS No. : 489413-54-9

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250 mg Obtenir un devis 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
500 mg   Obtenir un devis  
1 g   Obtenir un devis  
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Topoisomerase I/II inhibitor 7 Related Antibodies

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Topoisomerase Topo I Topo II DNA gyrase

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Description

Topoisomerase I/II inhibitor 7 (Compound 5h) is a Topoisomerase I/II inhibitor[1].

IC50 & Target[1]

Topoisomerase I

 

Topoisomerase II

 

Cellular Effect
Cell Line Type Value Description References
BT-474 IC50
> 50 μM
Compound: 5h
Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay
[PMID: 26988802]
HCT-15 IC50
> 50 μM
Compound: 5h
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay
[PMID: 26988802]
T47D IC50
> 50 μM
Compound: 5h
Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay
Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay
[PMID: 26988802]
Masse moléculaire

340.76

Formule

C18H13ClN2O3
CAS No.
SMILES

O=C(N1N=C(CC1C2=CC=CO2)C3=CC=C(Cl)C=C3)C4=CC=CO4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Topoisomerase I/II inhibitor 7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Topoisomerase I/II inhibitor 7489413-54-9TopoisomeraseCancerInhibitorinhibitorinhibit

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Cat. No.:
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