Topoisomerase IIα-IN-6
Topoisomerase IIα-IN-6 (Compound 47d) is an inhibitor of DNA topoisomerase IIα/β. Topoisomerase IIα-IN-6 inhibits human topoisomerase IIα and human topoisomerase IIβ with IC50 values of 0.67 µM and 0.55 µM, respectively. Topoisomerase IIα-IN-6 has stable metabolism.
For research use only. We do not sell to patients.
- CAS No.: 3042869-61-1
- Formula: C23H24Cl3N5O4
- Molecular Weight:540.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Topoisomerase Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
topoisomerase II alpha 0.67 μM (IC50) |
Chemical Information
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CAS No. 3042869-61-1
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Molecular Weight 540.83
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Formula C23H24Cl3N5O4
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SMILES
CC1=C(C(Cl)=C(N1)C(NC2=CC=C(C=C2OCC3=CC=C(C=C3)C(NCCN)=O)C(N)=O)=O)Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)