Tricyclohexylphosphonium tetrafluoroborate
Based on 1 Customer Validation
Tricyclohexylphosphonium tetrafluoroborate is an intermediate. Tricyclohexylphosphonium tetrafluoroborate can be used to synthesize anticancer agents (Compounds 7a, 7e). Tricyclohexylphosphonium tetrafluoroborate can be used in the research of leukemia, lung cancer, liver cancer, breast cancer and colon cancer.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 58656-04-5
- Formula: C18H34BF4P
- Molecular Weight:368.24
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-Y0091
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HY-Y0006
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HY-W009410
Amphos -
HY-34614
Tricyclohexylphosphine -
HY-70026
Tri(2-methylphenyl)phosphine -
HY-W007323
JohnPhos -
HY-W002925
DavePhos -
HY-W013327
Cyclohexyldiphenylphosphine -
HY-W002849
Cyjohnphos -
HY-W009062
MePhos -
HY-W008707
Tris(4-fluorophenyl)phosphine
Biological Activity
Description
Chemical Information
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CAS No. 58656-04-5
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Appearance Solid
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Molecular Weight 368.24
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Formula C18H34BF4P
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Color White to off-white
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SMILES
F[B-](F)(F)F.[PH+](C1CCCCC1)(C2CCCCC2)C3CCCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : ≥ 200 mg/mL (543.12 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 33.33 mg/mL (90.51 mM; Need ultrasonic)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (13.58 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (13.58 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 2.7156 mL | 13.5781 mL | 27.1562 mL | 67.8905 mL |
| 5 mM | 0.5431 mL | 2.7156 mL | 5.4312 mL | 13.5781 mL | |
| 10 mM | 0.2716 mL | 1.3578 mL | 2.7156 mL | 6.7891 mL | |
| 15 mM | 0.1810 mL | 0.9052 mL | 1.8104 mL | 4.5260 mL | |
| 20 mM | 0.1358 mL | 0.6789 mL | 1.3578 mL | 3.3945 mL | |
| 25 mM | 0.1086 mL | 0.5431 mL | 1.0862 mL | 2.7156 mL | |
| 30 mM | 0.0905 mL | 0.4526 mL | 0.9052 mL | 2.2630 mL | |
| 40 mM | 0.0679 mL | 0.3395 mL | 0.6789 mL | 1.6973 mL | |
| 50 mM | 0.0543 mL | 0.2716 mL | 0.5431 mL | 1.3578 mL | |
| 60 mM | 0.0453 mL | 0.2263 mL | 0.4526 mL | 1.1315 mL | |
| 80 mM | 0.0339 mL | 0.1697 mL | 0.3395 mL | 0.8486 mL | |
| DMSO | 100 mM | 0.0272 mL | 0.1358 mL | 0.2716 mL | 0.6789 mL |
Tricyclohexylphosphonium tetrafluoroborate Related Classifications
HY-59270 Related Classifications
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