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Cat. No.: HY-153431

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TRV-1387

TRV-1387 is a benzofurazan that inhibits the aggregation of tau and amyloid-β.

For research use only. We do not sell to patients.

CAS No.: 1569645-63-1
Formula: C₂₃H₂₅F₃N₄O₂
Molecular Weight:446.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

TRV-1387 Chemical Structure

CAS No.: 1569645-63-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

TRV-1387 is a benzofurazan that inhibits the aggregation of tau and amyloid-β^[1].

Chemical Information

CAS No. 1569645-63-1
Molecular Weight 446.47
Formula C₂₃H₂₅F₃N₄O₂
SMILES

FC(F)(C(C1=CC=CC(C2=CC3=NON=C3C(N4CCC(CC4)N5CCCC5)=C2)=C1)O)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rauch JN, et al. Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules. Cold Spring Harb Perspect Med. 2017 Jul 5;7(7):a024034. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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