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Cat. No.: HY-115970

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Tubulin inhibitor 21

Tubulin inhibitor 21 (compound 6f), a chalcone- and melatonin- based hybrid, is a potent tubulin inhibitor. Tubulin inhibitor 21 induces a remarkable cytotoxic activity toward SW480 cells (IC₅₀=0.26 μM) with lower effect against nonmalignant cells.

For research use only. We do not sell to patients.

Formula: C₂₈H₂₅N₃O₄S
Molecular Weight:499.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Tubulin inhibitor 21 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Molecular Weight 499.58
Formula C₂₈H₂₅N₃O₄S
SMILES

O=C(C1=CC=C(C=C1)OCCCSC2=NN=C(O2)CCC3=CNC4=C3C=CC=C4)/C=C/C5=CC=CO5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Andrés F. Yepes, et al. New class of hybrids based on chalcone and melatonin: a promising therapeutic option for the treatment of colorectal cancer. Medicinal Chemistry Research volume 30, pages2240–2255 (2021).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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