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SSNA1 - SS nuclear autoantigen 1 Gene

Also Known as N14; NA14; NA-14

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 8636

About SSNA1

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,188,676-137,190,366 (from NCBI)

This gene has 4 transcripts (splice variants) and 117 orthologues. Ubiquitous expression in testis (RPKM 42.7), kidney (RPKM 20.7) and 25 other tissues.

Summary

Enables identical protein binding activity. Predicted to act upstream of or within ciliary receptor clustering involved in smoothened signaling pathway and intraciliary transport. Located in centrosome. [provided by Alliance of Genome Resources, Apr 2022]

SSNA1 Products (1)

mRNA	Protein	Name
NM_003731.3	NP_003722.2	microtubule nucleation factor SSNA1

Protein Preferred Names	Protein Names
microtubule nucleation factor SSNA1	Sjogren syndrome nuclear autoantigen 1

SSNA1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	SSNA1	O43805	TCEANC	Homo sapiens	Q8N8B7-2	Validated Y2H	32296183
Intra	SSNA1	O43805	EHHADH	Homo sapiens	Q08426	Y2H Array	31515488
Intra	SSNA1	O43805	EHHADH	Homo sapiens	Q08426	Y2H Prey Pooling	25416956
Intra	SSNA1	O43805	RNF4	Homo sapiens	P78317	Y2H Array	32296183
Intra	SSNA1	O43805	RNF4	Homo sapiens	P78317	Validated Y2H	32296183
Intra	SSNA1	O43805	RNF4	Homo sapiens	P78317	Y2H Prey Pooling	32296183
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	Y2H	21516116
Intra	SSNA1	O43805	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	32296183
Intra	SSNA1	O43805	LNX1	Homo sapiens	Q8TBB1	Y2H Array	25416956
Intra	SSNA1	O43805	TBC1D7	Homo sapiens	Q9P0N9	Y2H Array	31515488
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	Validated Y2H	27107012
Intra	SSNA1	O43805	LNX1	Homo sapiens	Q8TBB1	Y2H Array	29892012
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	Y2H Prey Pooling	32296183
Intra	SSNA1	O43805	TBC1D7	Homo sapiens	Q9P0N9	Validated Y2H	32296183
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	Y2H	27107012
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	Validated Y2H	32296183
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	Y2H Array	25416956
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	SLC	27107012
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	BFG-2H	27107012
Intra	SSNA1	O43805	SSNA1	Homo sapiens	O43805	Y2H Array	32296183
Intra	SSNA1	O43805	TXN2	Homo sapiens	Q99757	Validated Y2H	25416956
Intra	SSNA1	O43805	TXN2	Homo sapiens	Q99757	Validated Y2H	32296183
Intra	SSNA1	O43805	CDC37	Homo sapiens	Q16543	Validated Y2H	32296183
Intra	SSNA1	O43805	GOPC	Homo sapiens	Q9HD26	Y2H Prey Pooling	25416956
Intra	SSNA1	O43805	GOPC	Homo sapiens	Q9HD26	Y2H Array	25416956
Intra	SSNA1	O43805	LCA5	Homo sapiens	Q86VQ0	TAP	27173435
Intra	SSNA1	O43805	SDCBP	Homo sapiens	O00560	Validated Y2H	25416956
Intra	SSNA1	O43805	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	32296183
Intra	SSNA1	O43805	PICK1	Homo sapiens	Q9NRD5	Validated Y2H	32296183
Intra	SSNA1	O43805	TCEANC	Homo sapiens	Q8N8B7	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Paralytic Squint	Paralytic Strabismus Incomitant Dissociation
Sjogren Syndrome	Sicca Syndrome Sjogren'S Syndrome Sjögren Syndrome Sjogren-Gougerot Syndrome Keratoconjunctivitis Sicca Sjögren'S Syndrome Xerodermosteosis Dacryosialoadenopathia Atrophicans Gougerot-Houwer-Sjogren Syndrome Gougerot-Sjogren Syndrome Keratoconjunctivitis Sicca-Xerostomia Secreto-Inhibitor-Xerodermostenosis Primary Sjogren Syndrome Primary Sjogren-Gougerot Syndrome Sjogrens Syndrome Primary Sjogrens Syndrome Dry Eye Syndromes
Spindle Cell Hemangioma	Sch Spindle Cell Hemangioendothelioma
Hereditary Spastic Paraplegia	Familial Spastic Paraplegia Hereditary Spastic Paraparesis Strumpell-Lorrain Disease Familial Spastic Paraparesis Hsp Spg Strümpell-Lorrain Disease Spastic Paraplegia, Hereditary French Settlement Disease Strumpell-Lorrain Syndrome Fsp Spastic Paraplegia, Familial Spastic Paraplegia Hereditary Spastic Paraplegia 3, Autosomal Dominant Spastic Paraparesis Hereditary Spastic Paralysis Familial Spastic Paralysis Hereditary Spastic Ataxia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-148663	Mitogenic Pentapeptide	Activator	/	Unkown
HY-RS13812	SSNA1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SSNA1	VGNC	VGNC:35316
Felis catus	SSNA1	VGNC	VGNC:65707
Mus musculus	SSNA1	MGD	MGI:1915725
Canis familiaris	SSNA1	VGNC	VGNC:46835
Rattus norvegicus	SSNA1	RGD	RGD:1310259
Others	SSNA1	NCBI