2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. Tyk2-IN-16

Tyk2-IN-16 is a selective and potent TYK2 inhibitor with an IC50 of <10 nM for TYK2-JH2. Tyk2-IN-16 inhibits pSTAT4 with an IC50 of <10 nM in NK92 cells (WO2023220046A1; compound 184).

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Tyk2-IN-16

Tyk2-IN-16 Estructura química

No. CAS : 3010874-30-0

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Tyk2-IN-16 Related Antibodies

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Descripciòn

Tyk2-IN-16 is a selective and potent TYK2 inhibitor with an IC50 of <10 nM for TYK2-JH2. Tyk2-IN-16 inhibits pSTAT4 with an IC50 of <10 nM in NK92 cells (WO2023220046A1; compound 184)[1].

IC50 & Target[1]

Tyk2 JH2

<10 nM (IC50)

Peso molecular

426.42

Fòrmula

C20H20F2N8O
No. CAS
SMILES

N#CC1(CN(CC1)C2=NN(C3=C2C=NC(NC(C)=O)=C3)C4=NC=CC(C(F)(C)F)=N4)C
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Room temperature in continental US; may vary elsewhere.
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Tyk2-IN-16 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tyk2-IN-163010874-30-0JAKJanus kinaseTYK2 inhibitorpSTAT4TYK2-JH2Inhibitorinhibitorinhibit

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Nombre del producto:
Tyk2-IN-16
Cat. No.:
HY-163304
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