UHMCP1 dihydrochloride
UHMCP1 dihydrochloride is a potent UHM domain splicing inhibitor with a Kd value of 79 μM. UHMCP1 dihydrochloride prevents the SF3b155/U2AF65 interaction. UHMCP1 dihydrochloride impacts cell viability and RNA splicing.
For research use only. We do not sell to patients.
- CAS No.: 2925647-93-2
- Formula: C19H29Cl2N3
- Molecular Weight:370.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Kd: 79 µM (UHM domain)[1]
UHMCP1 dihydrochloride (0-100 μM; 24 h) impacts cell viability and splicing with an EC50 value of 140 μM in HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK293 cells
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Concentration:0-100 µM
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Incubation Time:24 h
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Result:Inhibited cell viability with an EC50 value of 140 µM.
Chemical Information
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CAS No. 2925647-93-2
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Molecular Weight 370.36
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Formula C19H29Cl2N3
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SMILES
CC(N(C[C@]1([H])CC2)C[C@]2([H])[C@H]1N)CCC3=CNC4=CC=CC=C34.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)