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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
liposome formulations
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "liposome formulations" in MCE Product Catalog:
Cat. No.: HY-W440911
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DSPE-PEG2000-Cy5 is a Cy5 (HY-D0821) fluorophore-labeled conjugate of distearoylphosphatidylethanolamine and polyethylene glycol, as well as a liposome component. The Cy5 fluorophore is commonly used for labeling proteins and nucleic acids in imaging, flow cytometry and genomic applications. DSPE-PEG2000-Cy5 supports cell membrane modification, in vivo tumor targeting research and long-term in vivo circulation of its liposomal formulations (Ex/Em=633/670 nm) .
DPyPE is a neutral phosphatidylethanolamine lipid composed of a polyisoprene alkyl chain with two pyridine-containing phosphine ligands. DPyPE is mainly used in liposome formulations and to enhance the efficiency of gene delivery in vitro and in vivo. For example, DPyPE can be mixed with cationic lipids such as VC1052 (HY-156616) (in a 1:1 ratio) to form the vaccine adjuvant Vaxfectin (HY-142998). DPyPE assists VC1052 in binding to negatively charged pDNA to form a uniform liposome complex by regulating the fluidity and stability of the liposome membrane .
Synonyms: 16:0 PEG2000 PE ammonium; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
DPPE-PEG2000 ammonium (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG2000 ammonium enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG2000 ammonium helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG2000 ammonium serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .
Cat. No.: HY-144012H
CAS No.: 474922-84-4
Synonyms: 16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
DPPE-PEG5000 (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG5000 enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG5000 helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG5000 serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .
1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a carboxylic acid lipid targeting agent. 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate serves as a carboxylic acid lipid substitute for phosphatidylserine and is used to control liposome surface modification, and the modified liposomes exhibit in vivo compound release behavior similar to that of unmodified liposomes. Liposomes containing 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate specifically target bone marrow. 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is used in the study of breast cancer .
1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-Distearoyl-sn-glycero-3-phosphate, sodium salt has unique chemical properties that make it an effective tool for encapsulating drugs and delivering them to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
Cat. No.: HY-177849
Synonyms: Amphotericin B liposome
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Liposomal Amphotericin B (Amphotericin B liposome) is a liposomal formulation of Amphotericin B (HY-B0221) that can cross the blood-brain barrier. Liposomal Amphotericin B binds to fungal cell walls and releases Amphotericin B to bind Ergosterol (HY-N0181), inducing pore formation, ion leakage, and fungal cell death. Liposomal Amphotericin B exhibits fungicidal activity against a broad spectrum of fungal pathogens, also shows activity against Leishmania, and the liposomal formulation has lower acute and chronic toxicity as well as a lower risk of fungal resistance .
1,2-dioctanoyl-sn-glycero-3-phosphocholine, is a phospholipid commonly used as a component of liposome formulations and drug delivery systems. 1,2-dioctanoyl-sn-glycero-3-phosphocholine has unique chemical properties that allow it to form stable bilayers and vesicles, allowing drug encapsulation and delivery to specific targets in the body. It acts as a stabilizer and emulsifier, which can improve the solubility and bioavailability of drugs.
Cat. No.: HY-185588
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Anionic Liposomes (DOPG, 10mM) is a Phosphatidylglycerol (PG)-based-100% DOPG formulation. Anionic Liposomes (DOPG, 10mM) can be used for drug delivery and lipid-protein interactions.
Cat. No.: HY-177191
CAS No.: 185463-22-3
Synonyms: L-α-Dimyristoylphosphatidylglycerol; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol
DMPG (L-α-Dimyristoylphosphatidylglycerol; 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol) is a phospholipid that can be used for preparing formulations such as liposomes or gels. DMPG can be used in the research of drug delivery .
Cat. No.: HY-W332450
CAS No.: 126-75-0
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Demeton-S is an organophosphate insecticide. Demeton-S inhibits butyrylcholinesterase and acetylcholinesterase activity .
Cat. No.: HY-160713
CAS No.: 27297-42-3
Synonyms: NSSL-BMS
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Betamethasone succinate (NSSL-BMS) is a nano-formulation that can cross the blood-brain barrier. Betamethasone succinate is prepared by encapsulating the Betamethasone (HY-13570) semi-succinate in PEG-liposomes. Betamethasone succinate utilizes the enhanced permeation and retention effects of liposomes to target and deliver the potent glucocorticoid to the inflammatory sites. Betamethasone succinate inhibits the secretion of pro-inflammatory cytokines (such as TNF-α and IL-6) while maintaining the level of anti-inflammatory cytokine TGF-β. Betamethasone succinate can be used in the research of arthritis and cerebral malaria .
Cat. No.: HY-185404
DSPE-PEG8-OH is a monodisperse lipid-polyethylene glycol conjugate featuring a hydrophobic 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) anchor, an 8-unit discrete (PEG8) spacer, and a terminal hydroxyl (-OH) group. DSPE-PEG8-OH is primarily used in liposome formulation, nanoparticle surface modification, and targeted drug delivery systems.
Cat. No.: HY-15772G
CAS No.: 1421373-65-0
Synonyms: AZD-9291 (GMP); Mereletinib (GMP)
Cat. No.: HY-15772GL
CAS No.: 1421373-65-0
Synonyms: AZD-9291 (GMP Like); Mereletinib (GMP Like)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
