Wnt/β-catenin agonist 4
Based on 1 Customer Validation
Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 912784-79-3
- Formula: C16H15FN4O2
- Molecular Weight:314.31
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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High-Throughput Bioactive Compound Library
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Biological Activity
Wnt[1]
Wnt/β-catenin agonist 4 (Derivative 83) (120 μM; 24 h) shows 1049% β-catenin activity in HEK293 and SW480 cells[1].
Wnt/β-catenin agonist 4 (11 μM; 4 days) shows 2848% ALP activity on differentiation of ST2 cell line into osteoblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 912784-79-3
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Appearance Solid
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Molecular Weight 314.31
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Formula C16H15FN4O2
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Color Yellow to brown
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SMILES
O=C(C1=NOC(C2=CC=C(F)C=C2)=C1)NCCCN3C=CN=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 125 mg/mL (397.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1816 mL | 15.9079 mL | 31.8157 mL | 79.5393 mL |
| 5 mM | 0.6363 mL | 3.1816 mL | 6.3631 mL | 15.9079 mL | |
| 10 mM | 0.3182 mL | 1.5908 mL | 3.1816 mL | 7.9539 mL | |
| 15 mM | 0.2121 mL | 1.0605 mL | 2.1210 mL | 5.3026 mL | |
| 20 mM | 0.1591 mL | 0.7954 mL | 1.5908 mL | 3.9770 mL | |
| 25 mM | 0.1273 mL | 0.6363 mL | 1.2726 mL | 3.1816 mL | |
| 30 mM | 0.1061 mL | 0.5303 mL | 1.0605 mL | 2.6513 mL | |
| 40 mM | 0.0795 mL | 0.3977 mL | 0.7954 mL | 1.9885 mL | |
| 50 mM | 0.0636 mL | 0.3182 mL | 0.6363 mL | 1.5908 mL | |
| 60 mM | 0.0530 mL | 0.2651 mL | 0.5303 mL | 1.3257 mL | |
| 80 mM | 0.0398 mL | 0.1988 mL | 0.3977 mL | 0.9942 mL | |
| 100 mM | 0.0318 mL | 0.1591 mL | 0.3182 mL | 0.7954 mL |
Wnt/β-catenin agonist 4 Related Classifications
HY-151520 Related Classifications
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