WRN inhibitor 10
WRN inhibitor 10 (Compound P24) is an inhibitor for the Werner helicase WRN with an IC50 of 1.1 nM. WRN inhibitor 10 inhibits the proliferation of cancer cell SW48 with IC50 of 39 nM. WRN inhibitor 10 exhibits good liver microsomal stability and film permeability. WRN inhibitor 10 exhibits good pharmacokinetic characteristics in CD-1 mice.
For research use only. We do not sell to patients.
- CAS No.: 3049092-06-7
- Formula: C31H29BrClN9O5S
- Molecular Weight:755.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
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Helicase |
Chemical Information
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CAS No. 3049092-06-7
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Molecular Weight 755.04
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Formula C31H29BrClN9O5S
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SMILES
O=C(N1CCN(CC1)C2=C(N(C3=NC(C4=CC5=C(S4)COC5)=NN3C2=O)CC(NC6=CC=C(C=C6Cl)Br)=O)CC)C7=NC=NC(C)=C7O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)