1. Cytoskeleton
  2. Integrin
  3. αvβ1 integrin-IN-1

αvβ1 integrin-IN-1 

Cat. No.: HY-100445
Handling Instructions

αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects.

For research use only. We do not sell to patients.

αvβ1 integrin-IN-1 Chemical Structure

αvβ1 integrin-IN-1 Chemical Structure

CAS No. : 1689540-62-2

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Description

αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].

IC50 & Target

IC50: 0.63 nM (αvβ1 integrin)[1]

In Vitro

αvβ1 integrin-IN-1 (Compound C8) significantly reduces the fibrotic markers in mouse model for liver and lung fibrosis[1].

Molecular Weight

558.65

Formula

C₂₆H₃₄N₆O₆S

CAS No.

1689540-62-2

SMILES

O=C(O)[[email protected]](CC1=CC=C(NC(CCCCNC(N)=N)=O)C=C1)NC([[email protected]]2N(S(=O)(C3=CC=CC=C3)=O)CCC2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

αvβ1 integrin-IN-1Integrinαvβ1AntifibroticFibrosisInhibitorinhibitorinhibit

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