1. Cytoskeleton
  2. Integrin

Integrin Antagonists 27 

Cat. No.: HY-18668
Handling Instructions

Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent.

For research use only. We do not sell to patients.

Integrin Antagonists 27 Chemical Structure

Integrin Antagonists 27 Chemical Structure

CAS No. : 593274-97-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 462 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg USD 2520 Get quote
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • References

Description

Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. Target: Integrin in vitro: Integrin Antagonists 27 is treated with a panel of cancer cell-lines (breast cancer cell line MDA-MB-435, breast cancer cell lines MCF-7, mouse fibroblast NIH3T3, ovarian cancer cell line HEY, lung cancer cell line NCI-H1975) with all IC50 of >20 uM.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.2500 mL 11.2501 mL 22.5002 mL
5 mM 0.4500 mL 2.2500 mL 4.5000 mL
10 mM 0.2250 mL 1.1250 mL 2.2500 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

444.44

Formula

C₂₄H₂₀N₄O₅

CAS No.

593274-97-6

SMILES

O=C(O)C1=CC=CC(N2C(/C=C(C(N3CC(NC4=CC=C(C)C=C4)=O)=O)\NC3=O)=CC=C2)=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Integrin Antagonists 27
Cat. No.:
HY-18668
Quantity: