1,3-Bis(diphenylphosphino)propane
Based on 1 Customer Validation
1,3-Bis (diphenylphosphino) propane (1,3-DPPP) is a Pd2+-targeting ligand and anticancer agent. 1,3-Bis (diphenylphosphino) propane forms stable Pd2+ complexes with acetate or trifluoroacetate auxiliary ligands. 1,3-Bis (diphenylphosphino) propane exhibits anticancer activity against colon cancer. 1,3-Bis (diphenylphosphino) propane can be used in research related to breast cancer, lung adenocarcinoma, prostate cancer and Gram-positive bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 6737-42-4
- Formula: C27H26P2
- Molecular Weight:412.45
-
Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
-
HY-34614
Tricyclohexylphosphine
-
HY-Y0006
XPhos
-
HY-W002925
DavePhos
-
HY-W007323
JohnPhos
-
HY-Y0091
Xantphos
-
HY-W007569
1,4-Bis(diphenylphosphino)butane
-
HY-34451
Tri-tert-butylphosphine tetrafluoroborate
-
HY-Y0003
(Rac)-BINAP
-
HY-70026
Tri(2-methylphenyl)phosphine
-
HY-W002849
Cyjohnphos
-
HY-W009062
MePhos
-
HY-W011500
TCEP hydrochloride
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
72 μM
Compound: 29
|
In vitro cytotoxicity against murine B16 melanoma cells
In vitro cytotoxicity against murine B16 melanoma cells
|
[PMID: 3681888] |
1,3-Bis(diphenylphosphino)propane (1.56-100 μM; 48 h) exhibits significant cytotoxic activity against human colon cancer HT-29 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:human lung cancer A549 cells, human breast cancer MCF-7 cells, human prostate cancer PC-3 cells, human colon cancer HT-29 cells, normal human breast MCF-10A cells
-
Concentration:1.56-100 μM
-
Incubation Time:48 h
-
Result:Displayed significantly higher cytotoxic activity on HT-29 cells (IC50: 7.5 μM).
Displayed an IC50 of 56.1 μM against A549 cells.
Chemical Information
-
CAS No. 6737-42-4
-
Appearance Solid
-
Molecular Weight 412.45
-
Formula C27H26P2
-
SMILES
C=1C=CC(=CC1)P(C=2C=CC=CC2)CCCP(C=3C=CC=CC3)C=4C=CC=CC4
-
Synonyms
1,3-DPPP
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1,3-Bis(diphenylphosphino)propane Related Classifications
HY-Y1375 Related Classifications
Powered by Bioz