6737-42-4
Chemical Structure
1,3-Bis(diphenylphosphino)propane
Synonym(s): 1,3-DPPP
- CAS No.: 6737-42-4
- Formula:C27H26P2
- Molecular Weight:412.45
IUPAC Name: 1,3-bis(diphenylphosphanyl)propane
InChIKey: LVEYOSJUKRVCCF-UHFFFAOYSA-N
SMILES: C=1C=CC(=CC1)P(C=2C=CC=CC2)CCCP(C=3C=CC=CC3)C=4C=CC=CC4
Biological Activity: 1,3-Bis (diphenylphosphino) propane (1,3-DPPP) is a Pd2+-targeting ligand and anticancer agent. 1,3-Bis (diphenylphosphino) propane forms stable Pd2+ complexes with acetate or trifluoroacetate auxiliary ligands. 1,3-Bis (diphenylphosphino) propane exhibits anticancer activity against colon cancer. 1,3-Bis (diphenylphosphino) propane can be used in research related to breast cancer, lung adenocarcinoma, prostate cancer and Gram-positive bacterial infections[1][2].
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1,3-Bis(diphenylphosphino)propane | 1,3-Bis (diphenylphosphino) propane (1,3-DPPP) is a Pd2+-targeting ligand and anticancer agent. 1,3-Bis (diphenylphosphino) propane forms stable Pd2+ complexes with acetate or trifluoroacetate auxiliary ligands. 1,3-Bis (diphenylphosphino) propane exhibits anticancer activity against colon cancer. 1,3-Bis (diphenylphosphino) propane can be used in research related to breast cancer, lung adenocarcinoma, prostate cancer and Gram-positive bacterial infections. | |||||||||||||||||||||
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References
- [1]. Yilmaz VT, et al. Structures and biochemical evaluation of silver(I) 5,5-diethylbarbiturate complexes with bis(diphenylphosphino)alkanes as potential antimicrobial and anticancer agents. Eur J Med Chem. 2017 Oct 20;139:901-916. [Content Brief] [Content Brief]
- [2]. Bianchini C, et al. Copolymerization of carbon monoxide with ethene catalyzed by palladium (II) complexes of 1, 3-bis (diphenylphosphino) propane ligands bearing different substituents on the carbon backbone[J]. Macromolecules, 1999, 32(13): 4183-4193.
