1,4-O-Diferuloylsecoisolariciresinol

Cat. No.: HY-N1275: Data Sheet Handling Instructions
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1,4-O-Diferuloylsecoisolariciresinol (compound 7) is a nature product that could be isolated from Hypericum nagasawae. 1,4-O-Diferuloylsecoisolariciresinol can be used in research of cancer.

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1,4-O-Diferuloylsecoisolariciresinol 화학구조

CAS No. : 56973-66-1

사이즈	재고	수량
1 mg	견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	견적 받기
50 mg	견적 받기

Synthetic products have potential research and development risk.

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

1,4-O-Diferuloylsecoisolariciresinol (compound 7) is a nature product that could be isolated from Hypericum nagasawae. 1,4-O-Diferuloylsecoisolariciresinol can be used in research of cancer^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	12 μg/mL Compound: 3	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 18603435]
A549	IC₅₀	7.1 μM Compound: 11b	Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
B16-F1	IC₅₀	12 μg/mL Compound: 3	Cytotoxicity against mouse B16F1 cells after 48 hrs by SRB assay Cytotoxicity against mouse B16F1 cells after 48 hrs by SRB assay	[PMID: 18603435]
B16-F10	IC₅₀	9.8 μM Compound: 11b	Cytotoxicity against mouse B16F10 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against mouse B16F10 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
COLO 205	IC₅₀	5.2 μg/mL Compound: 10	Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay Cytotoxicity against human COLO205 cells after 48 hrs by MTT assay	[PMID: 19606850]
HCT-15	IC₅₀	8.3 μM Compound: 11b	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
K562	IC₅₀	17.3 μg/mL Compound: 10	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 19606850]
K562	IC₅₀	19.9 μg/mL Compound: 10	Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay Cytotoxicity against human doxorubicin-resistant K562 cells after 48 hrs by MTT assay	[PMID: 19606850]
KB	IC₅₀	14.1 μg/mL Compound: 10	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 19606850]
MCF7	IC₅₀	5.9 μg/mL Compound: 10	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19606850]
SK-MEL-2	IC₅₀	10 μg/mL Compound: 3	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay	[PMID: 18603435]
SK-MEL-2	IC₅₀	8.3 μM Compound: 11b	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]
SK-OV-3	IC₅₀	21.7 μM Compound: 11b	Cytotoxicity against human SKOV3 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SKOV3 cells after 48 hrs by sulforhodamine B assay	[PMID: 21958542]

분자량

714.75

화학식

C₄₀H₄₂O₁₂

CAS No.

56973-66-1

SMILES

COC(C=C1C[C@@H](COC(/C=C/C2=CC(OC)=C(C=C2)O)=O)[C@H](COC(/C=C/C3=CC(OC)=C(C=C3)O)=O)CC4=CC(OC)=C(C=C4)O)=C(C=C1)O

Structure Classification

Initial Source

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Sun MX, et, al. [Chemical constituents from Hypericum curvisepalum]. Zhongguo Zhong Yao Za Zhi. 2021 Aug;46(15):3859-3864. Chinese. [Content Brief]