1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. Propionylpromazine hydrochloride

Propionylpromazine hydrochloride (Synonyms: Propiopromazine hydrochloride)

Cat. No.: HY-W040146 Purity: 99.38%
Handling Instructions

Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease.

For research use only. We do not sell to patients.

Propionylpromazine hydrochloride Chemical Structure

Propionylpromazine hydrochloride Chemical Structure

CAS No. : 7681-67-6

Size Price Stock Quantity
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1].

IC50 & Target

D2 Receptor

 

Molecular Weight

376.94

Formula

C₂₀H₂₅ClN₂OS

CAS No.

7681-67-6

SMILES

CCC(C(C=C1N2CCCN(C)C)=CC=C1SC3=C2C=CC=C3)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (221.07 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6529 mL 13.2647 mL 26.5294 mL
5 mM 0.5306 mL 2.6529 mL 5.3059 mL
10 mM 0.2653 mL 1.3265 mL 2.6529 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.52 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.52 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.38%

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Keywords:

PropionylpromazinePropiopromazineDopamine ReceptordopaminereceptorDRD2ParkinsondiseaseInhibitorinhibitorinhibit

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Product Name:
Propionylpromazine hydrochloride
Cat. No.:
HY-W040146
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