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Cat. No.: HY-116704

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11-Deoxyprostaglandin F2α

11-Deoxyprostaglandin F2α is an activator for TREK-2 channels with EC₅₀ of 0.294 μM. 11-Deoxyprostaglandin F2α inhibits the K2P channel TREK-1.

For research use only. We do not sell to patients.

CAS No.: 37786-06-4
Formula: C₂₀H₃₄O₄
Molecular Weight:338.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

11-Deoxyprostaglandin F2α Chemical Structure

CAS No.: 37786-06-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-114986

6-Keto-PGE1

Biological Activity

Description

11-Deoxyprostaglandin F2α is an activator for TREK-2 channels with EC₅₀ of 0.294 μM. 11-Deoxyprostaglandin F2α inhibits the K2P channel TREK-1^[1].

Chemical Information

CAS No. 37786-06-4
Molecular Weight 338.48
Formula C₂₀H₃₄O₄
SMILES

OC(CCC/C=C\C[C@@H]1[C@H](CC[C@@H]1O)/C=C/[C@@H](O)CCCCC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dadi PK,et al., Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx. ACS Chem Neurosci. 2017 Mar 15;8(3):558-568. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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References

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11-Deoxyprostaglandin F2α

6-Keto-PGE1